What does cosyntropin mean?
Definitions for cosyntropin
cosyn·tropin
This dictionary definitions page includes all the possible meanings, example usage and translations of the word cosyntropin.
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Wiktionary
cosyntropinnoun
A synthetic derivative of ACTH that is used in the ACTH stimulation test to evaluate and diagnose cortisol disorders.
Wikipedia
cosyntropin
Adrenocorticotropic hormone is used as a medication and as diagnostic agent in the ACTH stimulation test.: 316, 1165 : 84, 271 The form that is purified from pig pituitary glands is known as corticotropin: 316 is a medication and naturally occurring polypeptide tropic hormone produced and secreted by the anterior pituitary gland.: 84 The form that is made synthetically is tetracosactide, also known as synacthen, tetracosactrin and cosyntropin.: 1165 : 271 It consists of the first 24 (of a total of 39) amino acids of ACTH and retains full function of the parent peptide.: 1165 Tetracosactide stimulates the release of corticosteroids such as cortisol from the adrenal glands, and is used for the ACTH stimulation test to assess adrenal gland function.: 271
Wikidata
Cosyntropin
Cosyntropin is a synthetic derivative of adrenocorticotropic hormone that is used in the ACTH stimulation test to evaluate and diagnose cortisol disorders. Cosyntropin contains only the first 24 amino acids of ACTH but retains full function. In patients with low cortisol levels or symptoms of adrenocortical insufficiency, cosyntropin can be used to diagnose Addison's disease. A failure for serum cortisol levels to increase after administration of cosyntropin makes a diagnosis of primary adrenocortical insufficiency more likely. An increase in cortisol upon administration of cosyntropin rules out the condition. The test may also be used to assess the function of the adrenal glands after successful treatment for Cushing's syndrome. Cosyntropin is also used in the opposite situation, when there is aldosterone hypersecretion due to either a unilateral adrenal adenoma or bilateral adrenal hyperplasia. A procedure called adrenal venous sampling may be used pre-operatively to localize the source of aldosterone hypersecretion from either adrenal gland. A peripheral intravenous infusion of Cosyntropin before and during the procedure stimulates cortisol production and thereby verifies catheter position.
U.S. National Library of Medicine
Cosyntropin
A synthetic peptide that is identical to the 24-amino acid segment at the N-terminal of ADRENOCORTICOTROPIC HORMONE. ACTH (1-24), a segment similar in all species, contains the biological activity that stimulates production of CORTICOSTEROIDS in the ADRENAL CORTEX.
Numerology
Chaldean Numerology
The numerical value of cosyntropin in Chaldean Numerology is: 1
Pythagorean Numerology
The numerical value of cosyntropin in Pythagorean Numerology is: 6
Translations for cosyntropin
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- CosyntropinGerman
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"cosyntropin." Definitions.net. STANDS4 LLC, 2024. Web. 26 Apr. 2024. <https://www.definitions.net/definition/cosyntropin>.
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