Definitions for controlled clinical trial
con·trolled clin·i·cal tri·al

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1. controlled clinical trial

   Clinical trials are prospective biomedical or behavioral research studies on human participants designed to answer specific questions about biomedical or behavioral interventions, including new treatments (such as novel vaccines, drugs, dietary choices, dietary supplements, and medical devices) and known interventions that warrant further study and comparison. Clinical trials generate data on dosage, safety and efficacy. They are conducted only after they have received health authority/ethics committee approval in the country where approval of the therapy is sought. These authorities are responsible for vetting the risk/benefit ratio of the trial—their approval does not mean the therapy is 'safe' or effective, only that the trial may be conducted. Depending on product type and development stage, investigators initially enroll volunteers or patients into small pilot studies, and subsequently conduct progressively larger scale comparative studies. Clinical trials can vary in size and cost, and they can involve a single research center or multiple centers, in one country or in multiple countries. Clinical study design aims to ensure the scientific validity and reproducibility of the results. Costs for clinical trials can range into the billions of dollars per approved drug. The sponsor may be a governmental organization or a pharmaceutical, biotechnology or medical device company. Certain functions necessary to the trial, such as monitoring and lab work, may be managed by an outsourced partner, such as a contract research organization or a central laboratory. Only 10 percent of all drugs started in human clinical trials become approved drugs.

U.S. National Library of MedicineRate this definition:0.0 / 0 votes

1. Controlled Clinical Trial

   Work consisting of a clinical trial involving one or more test treatments, at least one control treatment, specified outcome measures for evaluating the studied intervention, and a bias-free method for assigning patients to the test treatment. The treatment may be drugs, devices, or procedures studied for diagnostic, therapeutic, or prophylactic effectiveness. Control measures include placebos, active medicine, no-treatment, dosage forms and regimens, historical comparisons, etc. When randomization using mathematical techniques, such as the use of a random numbers table, is employed to assign patients to test or control treatments, the trial is characterized as a RANDOMIZED CONTROLLED TRIAL.

How to pronounce controlled clinical trial?

1. Alex

   US English

   David

   US English

   Mark

   US English

   Daniel

   British

   Libby

   British

   Mia

   British

   Karen

   Australian

   Hayley

   Australian

   Natasha

   Australian

   Veena

   Indian

   Priya

   Indian

   Neerja

   Indian

   Zira

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   Oliver

   British

   Wendy

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   Tessa

   South African

How to say controlled clinical trial in sign language?

Numerology

1. Chaldean Numerology

   The numerical value of controlled clinical trial in Chaldean Numerology is: 2

2. Pythagorean Numerology

   The numerical value of controlled clinical trial in Pythagorean Numerology is: 7

Examples of controlled clinical trial in a Sentence

1. Peter Salama:

   We are planning a randomized, controlled clinical trial, and we expect that to start within the time frame of this outbreak, so within the next couple of months in DRC.

References

1. ^ Wikipedia
   https://en.wikipedia.org/wiki/Controlled_Clinical_Trial