What does complement fixation tests mean?
Definitions for complement fixation tests
com·ple·ment fix·a·tion tests
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Wikipedia
complement fixation tests
The complement fixation test is an immunological medical test that can be used to detect the presence of either specific antibody or specific antigen in a patient's serum, based on whether complement fixation occurs. It was widely used to diagnose infections, particularly with microbes that are not easily detected by culture methods, and in rheumatic diseases. However, in clinical diagnostics labs it has been largely superseded by other serological methods such as ELISA and by DNA-based methods of pathogen detection, particularly PCR.
U.S. National Library of Medicine
Complement Fixation Tests
Serologic tests based on inactivation of complement by the antigen-antibody complex (stage 1). Binding of free complement can be visualized by addition of a second antigen-antibody system such as red cells and appropriate red cell antibody (hemolysin) requiring complement for its completion (stage 2). Failure of the red cells to lyse indicates that a specific antigen-antibody reaction has taken place in stage 1. If red cells lyse, free complement is present indicating no antigen-antibody reaction occurred in stage 1.
Numerology
Chaldean Numerology
The numerical value of complement fixation tests in Chaldean Numerology is: 9
Pythagorean Numerology
The numerical value of complement fixation tests in Pythagorean Numerology is: 9
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"complement fixation tests." Definitions.net. STANDS4 LLC, 2024. Web. 29 Apr. 2024. <https://www.definitions.net/definition/complement+fixation+tests>.
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