What does coagulase mean?
Definitions for coagulase
koʊˈæg yəˌleɪs, -ˌleɪzco·ag·u·lase
This dictionary definitions page includes all the possible meanings, example usage and translations of the word coagulase.
Princeton's WordNet
coagulasenoun
an enzyme that induces coagulation
Wiktionary
coagulasenoun
Any enzyme that induces coagulation
coagulasenoun
Specifically, the enzyme produced by various Staphylococcus species that converts fibrinogen to fibrin
Wikipedia
Coagulase
Coagulase is a protein enzyme produced by several microorganisms that enables the conversion of fibrinogen to fibrin. In the laboratory, it is used to distinguish between different types of Staphylococcus isolates. Importantly, S. aureus is generally coagulase-positive, meaning that a positive coagulase test would indicate the presence of S. aureus or any of the other 11 coagulase-positive Staphylococci. A negative coagulase test would instead show the presence of coagulase-negative organisms such as S. epidermidis or S. saprophyticus. However, it is now known that not all S. aureus are coagulase-positive. Whereas coagulase-positive Staphylococci are usually pathogenic, coagulase-negative Staphylococci are more often associated with opportunistic infection.It is also produced by Yersinia pestis.Coagulase reacts with prothrombin in the blood. The resulting complex is called staphylothrombin, which enables the enzyme to act as a protease to convert fibrinogen, a plasma protein produced by the liver, to fibrin. This results in clotting of the blood. Coagulase is tightly bound to the surface of the bacterium S. aureus and can coat its surface with fibrin upon contact with blood. The fibrin clot may protect the bacterium from phagocytosis and isolate it from other defenses of the host. The fibrin coat can therefore make the bacteria more virulent. Bound coagulase is part of the larger family of MSCRAMM adhesin proteins.
ChatGPT
coagulase
Coagulase is a type of enzyme that is produced by certain bacteria, like Staphylococcus aureus, which allows the bacteria to convert fibrinogen, a protein found in blood, into fibrin. This results in the clotting of blood or plasma that helps protect the bacteria from attack by the host's immune system. Coagulase can therefore contribute to the virulence of certain bacterial strains, and its presence is often used in diagnostic tests to differentiate them from other organisms.
Wikidata
Coagulase
Coagulase is a protein enzyme produced by several microorganisms that enables the conversion of fibrinogen to fibrin. In the laboratory, it is used to distinguish between different types of Staphylococcus isolates. Importantly, S. aureus is coagulase-positive, meaning that coagulase negativity excludes S. aureus. It is also produced by Yersinia pestis. Coagulase reacts with prothrombin in the blood. The resulting complex is called staphylothrombin, which enables the enzyme protease to convert fibrinogen to fibrin. This results in clotting of the blood. Coagulase is tightly bound to the surface of the bacterium S. aureus and can coat its surface with fibrin upon contact with blood. It has been proposed that fibrin-coated staphylococci resist phagocytosis, making the bacteria more virulent. Bound coagulase is part of the larger family of MSCRAMM.
U.S. National Library of Medicine
Coagulase
Enzymes that cause coagulation in plasma by forming a complex with human PROTHROMBIN. Coagulases are produced by certain STAPHYLOCOCCUS and YERSINIA PESTIS. Staphylococci produce two types of coagulase: Staphylocoagulase, a free coagulase that produces true clotting of plasma, and Staphylococcal clumping factor, a bound coagulase in the cell wall that induces clumping of cells in the presence of fibrinogen.
Matched Categories
Numerology
Chaldean Numerology
The numerical value of coagulase in Chaldean Numerology is: 5
Pythagorean Numerology
The numerical value of coagulase in Pythagorean Numerology is: 3
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Translations for coagulase
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"coagulase." Definitions.net. STANDS4 LLC, 2024. Web. 25 Apr. 2024. <https://www.definitions.net/definition/coagulase>.
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