What does celastrol mean?
Definitions for celastrol
celas·trol
This dictionary definitions page includes all the possible meanings, example usage and translations of the word celastrol.
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Wikipedia
Celastrol
Celastrol (tripterine) is a chemical compound isolated from the root extracts of Tripterygium wilfordii (Thunder god vine) and Celastrus regelii. Celastrol is a pentacyclic triterpenoid and belongs to the family of quinone methides. In mice, celastrol increase expression of IL1R1, which is the receptor for the cytokine interleukin-1 (IL-1). This suggests that celastrol exhibits its anti-obesity effects via a pro-inflammatory signaling pathway, as IL1R1 knock-out mice exposed to celastrol exhibit no leptin-sensitizing or anti-obesity effect.In in vitro and in vivo animal experiments, celastrol exhibits antioxidant, anti-inflammatory, anticancer, and insecticidal activities. It has been shown to have obesity-controlling effects in mice. Celastrol has also shown to possess (by inhibition of NF-κB in the hypothalamus) anti-diabetic effects on diabetic nephropathy and improve whole-body insulin resistance
Numerology
Chaldean Numerology
The numerical value of celastrol in Chaldean Numerology is: 4
Pythagorean Numerology
The numerical value of celastrol in Pythagorean Numerology is: 6
References
Translations for celastrol
From our Multilingual Translation Dictionary
- celastroloItalian
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"celastrol." Definitions.net. STANDS4 LLC, 2024. Web. 29 Apr. 2024. <https://www.definitions.net/definition/celastrol>.
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