Definitions for barrett's esophagus
bar·rett's esoph·a·gus

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1. Barrett's esophagus

   Barrett's esophagus is a condition in which there is an abnormal (metaplastic) change in the mucosal cells lining the lower portion of the esophagus, from stratified squamous epithelium to simple columnar epithelium with interspersed goblet cells that are normally present only in the small intestine and large intestine. This change is considered to be a premalignant condition because it is associated with a high incidence of further transition to esophageal adenocarcinoma, an often-deadly cancer.The main cause of Barrett's esophagus is thought to be an adaptation to chronic acid exposure from reflux esophagitis. Barrett's esophagus is diagnosed by endoscopy: observing the characteristic appearance of this condition by direct inspection of the lower esophagus; followed by microscopic examination of tissue from the affected area obtained from biopsy. The cells of Barrett's esophagus are classified into four categories: nondysplastic, low-grade dysplasia, high-grade dysplasia, and frank carcinoma. High-grade dysplasia and early stages of adenocarcinoma may be treated by endoscopic resection or radiofrequency ablation. Later stages of adenocarcinoma may be treated with surgical resection or palliation. Those with nondysplastic or low-grade dysplasia are managed by annual observation with endoscopy, or treatment with radiofrequency ablation. In high-grade dysplasia, the risk of developing cancer might be at 10% per patient-year or greater.The incidence of esophageal adenocarcinoma has increased substantially in the Western world in recent years. The condition is found in 5–15% of patients who seek medical care for heartburn (gastroesophageal reflux disease, or GERD), although a large subgroup of patients with Barrett's esophagus are asymptomatic. The condition is named after surgeon Norman Barrett (1903–1979) even though the condition was originally described by Philip Rowland Allison in 1946.

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1. Barrett's esophagus

   Barrett esophagus, sometimes called Barrett syndrome or columnar epithelium lined lower oesophagus, refers to an abnormal change in the cells of the lower portion of the esophagus. When the normal squamous epithelium lining of the esophagus is replaced by goblet cells, Barrett's esophagus is diagnosed. The medical significance of Barrett esophagus is its strong association with esophageal adenocarcinoma, a particularly lethal cancer. The main cause of Barrett esophagus is thought to be an adaptation to chronic acid exposure from reflux esophagitis. In the last 4 years, the incidence of esophageal adenocarcinoma has been increasing in the Western world. Barrett esophagus is found in 5–15% of patients who seek medical care for heartburn, although a large subgroup of patients with Barrett esophagus do not have symptoms. It is considered to be a premalignant condition because it is associated with an increased risk of esophageal cancer of about 0.5% per patient-year. If the cancer develops, it is very often deadly. Diagnosis of Barrett esophagus requires endoscopy and biopsy. The cells of Barrett esophagus, after biopsy, are classified into four general categories: non-dysplastic, low-grade dysplasia, high-grade dysplasia, and frank carcinoma. High-grade dysplasia and early stages of adenocarcinoma can be treated by endoscopic resection and new endoscopic therapies such as radiofrequency ablation, whereas advanced stages are generally advised to undergo surgical treatment. Non-dysplastic and low-grade patients are generally advised to undergo annual observation with endoscopy, with radiofrequency ablation as a therapeutic option. In high-grade dysplasia, the risk of developing cancer might be at 10% per patient-year or greater.

How to pronounce barrett's esophagus?

1. Alex

   US English

   David

   US English

   Mark

   US English

   Daniel

   British

   Libby

   British

   Mia

   British

   Karen

   Australian

   Hayley

   Australian

   Natasha

   Australian

   Veena

   Indian

   Priya

   Indian

   Neerja

   Indian

   Zira

   US English

   Oliver

   British

   Wendy

   British

   Fred

   US English

   Tessa

   South African

How to say barrett's esophagus in sign language?

Numerology

1. Chaldean Numerology

   The numerical value of barrett's esophagus in Chaldean Numerology is: 1

2. Pythagorean Numerology

   The numerical value of barrett's esophagus in Pythagorean Numerology is: 7

References

1. ^ Wikipedia
   https://en.wikipedia.org/wiki/Barrett'S_Esophagus
2. ^ Wikidata
   https://www.wikidata.org/w/index.php?search=barrett's esophagus