Definitions for asparaginase
as·parag·i·nase

Princeton's WordNetRate this definition:0.0 / 0 votes

1. asparaginase, Elsparnoun

   antineoplastic drug (trade name Elspar) sometimes used to treat lymphoblastic leukemia

WiktionaryRate this definition:0.0 / 0 votes

1. asparaginasenoun

   An enzyme that catalyzes the hydrolysis of asparagine to aspartic acid, used in chemotherapy.

WikipediaRate this definition:0.0 / 0 votes

1. Asparaginase

   Asparaginase is an enzyme that is used as a medication and in food manufacturing. As a medication, L-asparaginase is used to treat acute lymphoblastic leukemia (ALL) and lymphoblastic lymphoma (LBL). It is given by injection into a vein, muscle, or under the skin. A pegylated version is also available. In food manufacturing it is used to decrease acrylamide.Common side effects when used by injection include allergic reactions, pancreatitis, blood clotting problems, high blood sugar, kidney problems, and liver dysfunction. Use in pregnancy may harm the baby. As a food it is generally recognized as safe. Asparaginase works by breaking down the amino acid known as asparagine without which the cancer cells cannot make protein.The most common nonhematological adverse reactions of asparaginase erwinia chrysanthemi (recombinant) include abnormal liver test, nausea, musculoskeletal pain, infection, fatigue, headache, febrile neutropenia, pyrexia, hemorrhage (bleeding), stomatitis, abdominal pain, decreased appetite, drug hypersensitivity, hyperglycemia, diarrhea, pancreatitis, and hypokalemia.Asparaginase was approved for medical use in the United States in 1978. It is on the World Health Organization's List of Essential Medicines. It is often made from Escherichia coli (E. coli) or Erwinia chrysanthemi.

ChatGPTRate this definition:0.0 / 0 votes

1. asparaginase

   Asparaginase is an enzyme that is used as a medication for its ability to degrade asparagine, an amino acid that is essential for certain types of cancer cells to proliferate. Its primary use is in the treatment of acute lymphoblastic leukemia (ALL), a type of cancer that specifically requires asparagine. It catalyzes the hydrolysis of asparagine to aspartic acid and ammonia, depriving the cancer cells of the asparagine they need to grow and divide.

WikidataRate this definition:0.0 / 0 votes

1. Asparaginase

   Asparaginase is an enzyme that catalyzes the hydrolysis of asparagine to aspartic acid. Asparaginases are naturally occurring enzymes expressed and produced by microorganisms. Colaspase is also known as L-asparaginase.

U.S. National Library of MedicineRate this definition:0.0 / 0 votes

1. Asparaginase

   A hydrolase enzyme that converts L-asparagine and water to L-aspartate and NH3. EC 3.5.1.1.

Matched Categories

1. • Antineoplastic

How to pronounce asparaginase?

1. Alex

   US English

   David

   US English

   Mark

   US English

   Daniel

   British

   Libby

   British

   Mia

   British

   Karen

   Australian

   Hayley

   Australian

   Natasha

   Australian

   Veena

   Indian

   Priya

   Indian

   Neerja

   Indian

   Zira

   US English

   Oliver

   British

   Wendy

   British

   Fred

   US English

   Tessa

   South African

How to say asparaginase in sign language?

Numerology

1. Chaldean Numerology

   The numerical value of asparaginase in Chaldean Numerology is: 7

2. Pythagorean Numerology

   The numerical value of asparaginase in Pythagorean Numerology is: 3

Popularity rank by frequency of use

References

1. ^ Princeton's WordNet
   http://wordnetweb.princeton.edu/perl/webwn?s=asparaginase
2. ^ Wiktionary
   https://en.wiktionary.org/wiki/Asparaginase
3. ^ Wikipedia
   https://en.wikipedia.org/wiki/Asparaginase
4. ^ ChatGPT
   https://chat.openai.com
5. ^ Wikidata
   https://www.wikidata.org/w/index.php?search=asparaginase