Definitions for antihemophilic factor
an·ti·he·mophilic fac·tor

Princeton's WordNetRate this definition:0.0 / 0 votes

1. antihemophilic factor, antihaemophilic factor, antihemophilic globulin, antihaemophilic globulin, factor VIII, Hemofilnoun

   a coagulation factor (trade name Hemofil) whose absence is associated with hemophilia A

WikipediaRate this definition:0.0 / 0 votes

1. antihemophilic factor

   Factor VIII (FVIII) is an essential blood-clotting protein, also known as anti-hemophilic factor (AHF). In humans, factor VIII is encoded by the F8 gene. Defects in this gene result in hemophilia A, a recessive X-linked coagulation disorder. Factor VIII is produced in liver sinusoidal cells and endothelial cells outside the liver throughout the body. This protein circulates in the bloodstream in an inactive form, bound to another molecule called von Willebrand factor, until an injury that damages blood vessels occurs. In response to injury, coagulation factor VIII is activated and separates from von Willebrand factor. The active protein (sometimes written as coagulation factor VIIIa) interacts with another coagulation factor called factor IX. This interaction sets off a chain of additional chemical reactions that form a blood clot.Factor VIII participates in blood coagulation; it is a cofactor for factor IXa, which, in the presence of Ca2+ and phospholipids, forms a complex that converts factor X to the activated form Xa. The factor VIII gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity.People with high levels of factor VIII are at increased risk for deep vein thrombosis and pulmonary embolism. Copper is a required cofactor for factor VIII and copper deficiency is known to increase the activity of factor VIII.There is a formulation as a medication that is on the WHO Model List of Essential Medicines, the most important medications needed in a basic health system.

ChatGPTRate this definition:0.0 / 0 votes

1. antihemophilic factor

   The antihemophilic factor, also known as Factor VIII, is a protein that is essential for blood clotting. It is produced in the liver and circulates in the bloodstream in an inactive form, until a wound or injury causes it to be activated and perform its role in clotting. Deficiency or dysfunction of this factor leads to Hemophilia A, a genetic disorder that results in excessive bleeding and poor clot formation.

Matched Categories

1. • Coagulation Factor

How to pronounce antihemophilic factor?

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Numerology

1. Chaldean Numerology

   The numerical value of antihemophilic factor in Chaldean Numerology is: 6

2. Pythagorean Numerology

   The numerical value of antihemophilic factor in Pythagorean Numerology is: 7

References

1. ^ Princeton's WordNet
   http://wordnetweb.princeton.edu/perl/webwn?s=antihemophilic factor
2. ^ Wikipedia
   https://en.wikipedia.org/wiki/Antihemophilic_Factor
3. ^ ChatGPT
   https://chat.openai.com