Definitions for Ofloxacin
ofloxacin

WiktionaryRate this definition:0.0 / 0 votes

1. ofloxacinnoun

   A fluoroquinolone antibiotic.

WikipediaRate this definition:0.0 / 0 votes

1. Ofloxacin

   Ofloxacin is a quinolone antibiotic useful for the treatment of a number of bacterial infections. When taken by mouth or injection into a vein, these include pneumonia, cellulitis, urinary tract infections, prostatitis, plague, and certain types of infectious diarrhea. Other uses, along with other medications, include treating multidrug resistant tuberculosis. An eye drop may be used for a superficial bacterial infection of the eye and an ear drop may be used for otitis media when a hole in the ear drum is present.When taken by mouth, common side effects include vomiting, diarrhea, headache, and rash. Other serious side effect include tendon rupture, numbness due to nerve damage, seizures, and psychosis. Use in pregnancy is typically not recommended. Ofloxacin is in the fluoroquinolone family of medications. It works by interfering with the bacterium's DNA.Ofloxacin was patented in 1980 and approved for medical use in 1985. It is on the World Health Organization's List of Essential Medicines. Ofloxacin is available as a generic medication. In 2020, it was the 242nd most commonly prescribed medication in the United States, with more than 1 million prescriptions.

WikidataRate this definition:0.0 / 0 votes

1. Ofloxacin

   Ofloxacin is a synthetic chemotherapeutic antibiotic of the fluoroquinolone drug class considered to be a second-generation fluoroquinolone. The original brand, Floxin, has been discontinued by the manufacturer in the United States on 18 June 2009, though generic equivalents continue to be available. Ofloxacin was first patented in 1982 and received approval from the U.S. Food and Drug Administration on December 28, 1990. Ofloxacin is sold under a wide variety of brand names as well as generic drug equivalents, for oral and intravenous administration. Ofloxacin is also available for topical use, as eye drops and ear drops. Ofloxacin is a racemic mixture, which consists of 50% levofloxacin and 50% of its “mirror image” or enantiomer dextrofloxacin. When levofloxacin disks were not available in early clinical trials, a 5-pg ofloxacin disk was substituted. The U.S. Food and Drug Administration medical reviewers considered the two drugs to be one and the same and hence interchangeable. Like other quinolones, ofloxacin has been associated with a significant number of serious adverse drug reactions, such as tendon damage and peripheral neuropathy; such reactions may manifest long after therapy had been completed, and, in severe cases, may result in lifelong disabilities. Ofloxacin has also been associated with severe psychiatric adverse reactions.

U.S. National Library of MedicineRate this definition:0.0 / 0 votes

1. Ofloxacin

   A synthetic fluoroquinolone (FLUOROQUINOLONES) antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.

How to pronounce Ofloxacin?

1. Alex

   US English

   David

   US English

   Mark

   US English

   Daniel

   British

   Libby

   British

   Mia

   British

   Karen

   Australian

   Hayley

   Australian

   Natasha

   Australian

   Veena

   Indian

   Priya

   Indian

   Neerja

   Indian

   Zira

   US English

   Oliver

   British

   Wendy

   British

   Fred

   US English

   Tessa

   South African

How to say Ofloxacin in sign language?

Numerology

1. Chaldean Numerology

   The numerical value of Ofloxacin in Chaldean Numerology is: 4

2. Pythagorean Numerology

   The numerical value of Ofloxacin in Pythagorean Numerology is: 9

Popularity rank by frequency of use

References

1. ^ Wiktionary
   https://en.wiktionary.org/wiki/Ofloxacin
2. ^ Wikipedia
   https://en.wikipedia.org/wiki/Ofloxacin
3. ^ Wikidata
   https://www.wikidata.org/w/index.php?search=Ofloxacin