What does 1,3-dipolar cycloaddition mean?

Definitions for 1,3-dipolar cycloaddition
1,3-dipolar cycload·di·tion

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Wikipedia

  1. 1,3-Dipolar cycloaddition

    The 1,3-dipolar cycloaddition is a chemical reaction between a 1,3-dipole and a dipolarophile to form a five-membered ring. The earliest 1,3-dipolar cycloadditions were described in the late 19th century to the early 20th century, following the discovery of 1,3-dipoles. Mechanistic investigation and synthetic application were established in the 1960s, primarily through the work of Rolf Huisgen. Hence, the reaction is sometimes referred to as the Huisgen cycloaddition (this term is often used to specifically describe the 1,3-dipolar cycloaddition between an organic azide and an alkyne to generate 1,2,3-triazole). 1,3-dipolar cycloaddition is an important route to the regio- and stereoselective synthesis of five-membered heterocycles and their ring-opened acyclic derivatives. The dipolarophile is typically an alkene or alkyne, but can be other pi systems. When the dipolarophile is an alkyne, aromatic rings are generally produced.

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Numerology

  1. Chaldean Numerology

    The numerical value of 1,3-dipolar cycloaddition in Chaldean Numerology is: 7

  2. Pythagorean Numerology

    The numerical value of 1,3-dipolar cycloaddition in Pythagorean Numerology is: 2

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"1,3-dipolar cycloaddition." Definitions.net. STANDS4 LLC, 2024. Web. 29 Apr. 2024. <https://www.definitions.net/definition/1%2C3-dipolar+cycloaddition>.

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