What does nelarabine mean?
Definitions for nelarabine
nelara·bine
This dictionary definitions page includes all the possible meanings, example usage and translations of the word nelarabine.
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Wiktionary
nelarabinenoun
A particular drug used in chemotherapy.
Wikipedia
Nelarabine
Nelarabine, sold under the brand names Arranon (US) and Atriance (EU), is a chemotherapy medication used for the treatment of T-cell acute lymphoblastic leukemia (T-ALL) and T-cell lymphoblastic lymphoma (T-LBL). Nelarabine is a prodrug of arabinosylguanine nucleotide triphosphate (araGTP), a type of purine nucleoside analog, which causes inhibition of DNA synthesis and cytotoxicity. Pre-clinical studies suggest that T-cells are particularly sensitive to nelarabine. In October 2005, it was approved by the FDA for acute lymphoblastic leukemia and T-cell lymphoblastic lymphoma that has not responded to or has relapsed following treatment with at least two chemotherapy regimens. It was later approved in the European Union in October 2005. Complete responses have been achieved with this medication.
ChatGPT
nelarabine
Nelarabine is a chemotherapy drug used in the treatment of T-cell acute lymphoblastic leukemia and T-cell lymphoblastic lymphoma. It works by interfering with the DNA synthesis of cancer cells, leading to cell death.
Wikidata
Nelarabine
An arabinonucleoside antimetabolite with antineoplastic activity. Nelarabine is demethoxylated by adenosine deaminase to become biologically active 9-beta-D-arabinosylguanine (ara-G); ara-G incorporates into DNA, thereby inhibiting DNA synthesis and inducing an S phase-dependent apoptosis of tumor cells. (NCI04)
Numerology
Chaldean Numerology
The numerical value of nelarabine in Chaldean Numerology is: 3
Pythagorean Numerology
The numerical value of nelarabine in Pythagorean Numerology is: 9
Translations for nelarabine
From our Multilingual Translation Dictionary
- nelarabineArabic
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"nelarabine." Definitions.net. STANDS4 LLC, 2024. Web. 26 Apr. 2024. <https://www.definitions.net/definition/nelarabine>.
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