Definitions for nalorphineˈnæl ərˌfin, nælˈɔr fin
This page provides all possible meanings and translations of the word nalorphine
a narcotic antagonist (trade name Nalline) that counteracts the effects of narcotics (especially the effects of poisoning by morphine)
A drug used to reverse opioid overdose.
Origin: Contraction of N-allyl-normorphine.
Nalorphine, also known as N-allyl-normorphine, is a mixed opioid agonist-antagonist. It acts at two opioid receptors, at the mu receptor it has antagonistic effects and at the kappa receptors it exerts agonistic characteristics. It is used to reverse opioid overdose and in a challenge test to determine opioid dependence.
U.S. National Library of Medicine
A narcotic antagonist with some agonist properties. It is an antagonist at mu opioid receptors and an agonist at kappa opioid receptors. Given alone it produces a broad spectrum of unpleasant effects and it is considered to be clinically obsolete.
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