Definitions for naloxonenəˈlɒk soʊn, ˈnæl əkˌsoʊn
This page provides all possible meanings and translations of the word naloxone
Random House Webster's College Dictionary
nal•ox•onenəˈlɒk soʊn, ˈnæl əkˌsoʊn(n.)
an analgesic narcotic antagonist, C19H21NO4, used chiefly to counteract overdose.
Origin of naloxone:
1960–65; by shortening and rearrangement of dihydroxy-, morphinan-, and -one
a potent narcotic antagonist (trade name Narcan) especially effective with morphine
A drug used to counter the effects of an overdose on opioids (such as heroin or morphine).
Naloxone is an opioid inverse agonist drug developed by Sankyo in the 1960s. Naloxone is a drug used to counter the effects of opiate overdose, for example heroin or morphine overdose. Naloxone is specifically used to counteract life-threatening depression of the central nervous system and respiratory system. Naloxone is also experimentally used in the treatment for congenital insensitivity to pain with anhidrosis, an extremely rare disorder that renders one unable to feel pain. It is marketed under various trademarks including Narcan, Nalone, and Narcanti, and has sometimes been mistakenly called "naltrexate." It is not to be confused with naltrexone, an opioid receptor antagonist with qualitatively different effects, used for dependence treatment rather than emergency overdose treatment.
U.S. National Library of Medicine
A specific opiate antagonist that has no agonist activity. It is a competitive antagonist at mu, delta, and kappa opioid receptors.
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