Definitions for naloxone
nəˈlɒk soʊn, ˈnæl əkˌsoʊnnalox·one

Princeton's WordNetRate this definition:0.0 / 0 votes

1. naloxone, Narcannoun

   a potent narcotic antagonist (trade name Narcan) especially effective with morphine

WiktionaryRate this definition:0.0 / 0 votes

1. naloxonenoun

   A drug used to counter the effects of an overdose on opioids (such as heroin or morphine).

WikipediaRate this definition:0.0 / 0 votes

1. Naloxone

   Naloxone, sold under the brand name Narcan among others, is a medication used to reverse the effects of opioids. It is commonly used to counter decreased breathing in opioid overdose. Naloxone may also be combined with an opioid (in the same pill), to decrease the risk of misuse through injection. Effects begin within two minutes when given intravenously, and within five minutes when injected into a muscle. The medicine can also be administered by spraying it into a person's nose. Naloxone commonly blocks the effects of opioids for 30 to 90 minutes. Multiple doses may be required, as the duration of action of some opioids is greater than that of naloxone.Administration to opioid-dependent individuals may cause symptoms of opioid withdrawal, including restlessness, agitation, nausea, vomiting, a fast heart rate, and sweating. To prevent this, small doses every few minutes can be given until the desired effect is reached. In those with previous heart disease or taking medications that negatively affect the heart, further heart problems have occurred. It appears to be safe in pregnancy, after having been given to a limited number of women. Naloxone is a non-selective and competitive opioid receptor antagonist. It works by reversing the depression of the central nervous system and respiratory system caused by opioids. Naloxone generally has no effect on those not using opioids, has no abuse potential, and is recommended by the World Health Organization for distribution to anyone likely to encounter a fatal opioid overdose, including emergency personnel and friends and family members of those using opioids. Naloxone was patented in 1961 and approved for opioid overdose in the United States in 1971. It is on the World Health Organization's List of Essential Medicines. Naloxone is available as a generic medication. In April 2021, the U.S. Food and Drug Administration (FDA) approved a higher dose naloxone hydrochloride nasal spray product (Kloxxado) intended to treat opioid overdose from fentanyl and its analogues, which are many times stronger than heroin.

ChatGPTRate this definition:0.0 / 0 votes

1. naloxone

   Naloxone is a medication designed to rapidly reverse the effects of opioid drugs such as heroin, morphine, and methadone. It is an opioid antagonist, meaning it binds to the opioid receptors in the brain and blocks the effects of the opioid drugs, helping to restore normal respiratory function to someone whose breathing has slowed or stopped due to opioid overdose. It is often used in emergency situations to counteract the life-threatening effects of an overdose.

WikidataRate this definition:0.0 / 0 votes

1. Naloxone

   Naloxone is an opioid inverse agonist drug developed by Sankyo in the 1960s. Naloxone is a drug used to counter the effects of opiate overdose, for example heroin or morphine overdose. Naloxone is specifically used to counteract life-threatening depression of the central nervous system and respiratory system. Naloxone is also experimentally used in the treatment for congenital insensitivity to pain with anhidrosis, an extremely rare disorder that renders one unable to feel pain. It is marketed under various trademarks including Narcan, Nalone, and Narcanti, and has sometimes been mistakenly called "naltrexate." It is not to be confused with naltrexone, an opioid receptor antagonist with qualitatively different effects, used for dependence treatment rather than emergency overdose treatment.

U.S. National Library of MedicineRate this definition:0.0 / 0 votes

1. Naloxone

   A specific opiate antagonist that has no agonist activity. It is a competitive antagonist at mu, delta, and kappa opioid receptors.

Matched Categories

1. • Narcotic Antagonist

How to pronounce naloxone?

1. Alex

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   David

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   Mark

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   Daniel

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   Libby

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   Neerja

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How to say naloxone in sign language?

Numerology

1. Chaldean Numerology

   The numerical value of naloxone in Chaldean Numerology is: 2

2. Pythagorean Numerology

   The numerical value of naloxone in Pythagorean Numerology is: 1

Examples of naloxone in a Sentence

1. Thomas Farley:

   We have n’t seen a public health emergency like this in the last century, it’s time for us to rethink our assumptions, and consider options we had n’t seen before. Unlike similar efforts by other cities, the injection sites would not need City Council approval because they would be privately run. According to Philadelphia Public Health drug-related overdose deaths began to spoke in 2015 with the presence of fetanyl. ( Fox News) The sites would give drug addicts a safe haven to shoot up and would offer sterile injection equipment, including needles, and Naloxone. Fox News would also give referrals to treatment centers, social services clinics and wound care facilities. The idea comes as a paradigm shift in the nation’s effort to stem the tide of opioid-related deaths.Seattle and New York have been among places that have mulled similar measures, but the efforts stalled because of either legal or bureaucratic hurdles. Canada and Europe have operated similar types of facilities for the last few decades.

2. Rob Portman:

   This news is a positive step forward and I'm hopeful that it will increase access to naloxone, a critically-important overdose reversal drug that has saved tens of thousands of lives.

3. Edward Boyer:

   They require greater amounts of naloxone than they did in the past, and that’s because of the presence of fentanyl, i’ve had overdose [ patients ] that come in that just do n’t respond to naloxone at all because of either the amount or the potency of the opioid that they have on board.

4. Bobby Mukkamala:

   We believe that removing the prescription status of naloxone will allow for many emergency departments, health clinics, colleges, universities, high school and physicians offices to better distribute naloxone.

5. Anita Gupta:

   If you don’t use [naloxone] properly, the person may not get the full dose of the antidote, and it won’t work.

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References

1. ^ Princeton's WordNet
   http://wordnetweb.princeton.edu/perl/webwn?s=naloxone
2. ^ Wiktionary
   https://en.wiktionary.org/wiki/Naloxone
3. ^ Wikipedia
   https://en.wikipedia.org/wiki/Naloxone
4. ^ ChatGPT
   https://chat.openai.com
5. ^ Wikidata
   https://www.wikidata.org/w/index.php?search=naloxone