Definitions for ketoconazole
This page provides all possible meanings and translations of the word ketoconazole
A synthetic antifungal drug used especially in immunocompromised patients.
Ketoconazole is a synthetic, imidazole-derived antifungal medication used primarily to treat fungal infections. Ketoconazole is sold commercially as a tablet for oral administration, and in a variety of formulations, such as creams and shampoos, for topical administration. Ketoconazole is very lipophilic and tends to accumulate in fatty tissues. The less toxic and generally more effective triazole compounds fluconazole and itraconazole are usually preferred for internal use. Ketoconazole is best absorbed at highly acidic levels, so antacids or other causes of decreased stomach acid levels will lower the drug's absorption when taken orally. Absorption can be increased by taking it with an acidic beverage, such as cola.
U.S. National Library of Medicine
Broad spectrum antifungal agent used for long periods at high doses, especially in immunosuppressed patients.
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