1. (noun)difference the quality of being unlike or dissimilar
"there are many differences between jazz and rock"
2. (noun)deviation, divergence, departure, difference a variation that deviates from the standard or norm "the deviation from the mean"
3. (noun)dispute, difference, difference of opinion, conflict a disagreement or argument about something important
"he had a dispute with his wife"; "there were irreconcilable differences"; "the familiar conflict between Republicans and Democrats"
4. (noun)difference a significant change "the difference in her is amazing"; "his support made a real difference"