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Definition of 'debrisoquin'

U.S. National Library of Medicine

1. debrisoquin
An adrenergic neuron-blocking drug similar in effects to GUANETHIDINE. It is also noteworthy in being a substrate for a polymorphic cytochrome P-450 enzyme. Persons with certain isoforms of this enzyme are unable to properly metabolize this and many other clinically important drugs. They are commonly referred to as having a debrisoquin 4-hydroxylase polymorphism.

'debrisoquin' - Nearby Entries
death, sudden death, sudden, cardiac debaromyces debrisoquin decalcification, pathologic decamethonium compounds decanoates

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