What does cross-tolerance mean?
Definitions for cross-tolerance
cross-tol·er·ance
This dictionary definitions page includes all the possible meanings, example usage and translations of the word cross-tolerance.
Wikipedia
Cross-tolerance
Cross-tolerance is a phenomenon that occurs when tolerance to the effects of a certain drug produces tolerance to another drug. It often happens between two drugs with similar functions or effects—for example, acting on the same cell receptor or affecting the transmission of certain neurotransmitters. Cross-tolerance has been observed with pharmaceutical drugs such as anti-anxiety agents and illicit substances, and sometimes the two of them together. Often, a person who uses one drug can be tolerant to a drug that has a completely different function. This phenomenon allows one to become tolerant to a drug that they have never used before.
Wikidata
Cross-tolerance
Cross-tolerance refers to a pharmacological phenomenon, in which a patient being treated with a drug exhibits a physiological resistance to that medication as a result of tolerance to a pharmacologically similar drug. In other words, there is a decrease in response to one drug due to exposure to another similar acting drug. It is observed in treatment with antivirals, antibiotics and especially with opiate analgesics and many other medications including benzodiazepines. Cross-tolerance is particularly frequent among users of illicit drugs. For example, users with a high tolerance to the stimulant amphetamine may also exhibit a high tolerance to the structurally similar methamphetamine or other amphetamine-like stimulants. The phenomenon is also observed in cigarette smokers, in whom there is a demonstrably lessened sensitivity to the effects of caffeine. Cross-tolerance is also frequent in response to use of hallucinogens. General tolerance to the effects of tryptamines such as psilocybin, may be dramatic in response to repeated use, and this often translates into a tolerance to effects of other drugs such as Mescaline or DMT. This is also true of benzodiazepines such as alprazolam and clonazepam, even opiates as well.
Numerology
Chaldean Numerology
The numerical value of cross-tolerance in Chaldean Numerology is: 8
Pythagorean Numerology
The numerical value of cross-tolerance in Pythagorean Numerology is: 5
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"cross-tolerance." Definitions.net. STANDS4 LLC, 2024. Web. 26 Apr. 2024. <https://www.definitions.net/definition/cross-tolerance>.
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