What does cobblestone lissencephaly mean?
Definitions for cobblestone lissencephaly
cob·ble·stone lissencepha·ly
This dictionary definitions page includes all the possible meanings, example usage and translations of the word cobblestone lissencephaly.
Wikipedia
cobblestone lissencephaly
Lissencephaly (, meaning 'smooth brain') is a set of rare brain disorders whereby the whole or parts of the surface of the brain appear smooth. It is caused by defective neuronal migration during the 12th to 24th weeks of gestation resulting in a lack of development of brain folds (gyri) and grooves (sulci). It is a form of cephalic disorder. Terms such as agyria (no gyri) and pachygyria (broad gyri) are used to describe the appearance of the surface of the brain. Children with lissencephaly generally have significant developmental delays, but these vary greatly from child to child depending on the degree of brain malformation and seizure control. Life expectancy can be shortened, generally due to respiratory problems.
U.S. National Library of Medicine
Cobblestone Lissencephaly
The smooth pebbled appearance of the CEREBRAL CORTEX with a thickened cortex and reduced and abnormal white matter, which results from migration of heterotopic neurons beyond the marginal zone into the leptomeninges through gaps in the external BASEMENT MEMBRANE. There is also enlarged ventricles, underdeveloped BRAINSTEM and cerebellum, and absence of the CORPUS CALLOSUM. These abnormalities occur as a syndrome without other birth defects (cobblestone complex) or in other syndromes associated with congenital MUSCULAR DYSTROPHY, often involving the eye, such as the Walker-Warburg Syndrome, Fukuyama congenital muscular dystrophy, and muscle-eye-brain disease.
Numerology
Chaldean Numerology
The numerical value of cobblestone lissencephaly in Chaldean Numerology is: 2
Pythagorean Numerology
The numerical value of cobblestone lissencephaly in Pythagorean Numerology is: 8
Translations for cobblestone lissencephaly
From our Multilingual Translation Dictionary
- الحصى ليفينسفاليArabic
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"cobblestone lissencephaly." Definitions.net. STANDS4 LLC, 2024. Web. 28 Apr. 2024. <https://www.definitions.net/definition/cobblestone+lissencephaly>.
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