What does afterload mean?
Definitions for afterload
af·ter·load
This dictionary definitions page includes all the possible meanings, example usage and translations of the word afterload.
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Wiktionary
afterloadnoun
The load on a working muscle from a constant opposing force
Wikipedia
Afterload
Afterload is the pressure that the heart must work against to eject blood during systole (ventricular contraction). Afterload is proportional to the average arterial pressure. As aortic and pulmonary pressures increase, the afterload increases on the left and right ventricles respectively. Afterload changes to adapt to the continually changing demands on an animal's cardiovascular system. Afterload is proportional to mean systolic blood pressure and is measured in millimeters of mercury (mm Hg).
Wikidata
Afterload
Afterload is the tension or stress developed in the wall of the left ventricle during ejection. In other words, it is the end Load against which the heart contracts to eject blood. Afterload is readily broken into components; aortic pressure and/or the pressure the ventricle must overcome to eject blood. The greater the aortic/pulmonary pressure, the greater the after load on the left/right ventricle, respectively. Following Laplace's law, the tension upon the muscle fibers in the heart wall is the product of the pressure within the ventricle, multiplied by the volume within the ventricle, divided by the wall thickness. Therefore, when comparing a normal heart to a heart with a dilated left ventricle, if the aortic pressure is the same in both hearts, the dilated heart must create a greater tension to overcome the same aortic pressure to eject blood because it has a larger internal radius and volume. Thus, the dilated heart has a greater total load on the myocytes, i.e., has a higher afterload. Conversely, a hypertrophied left ventricle has a lower afterload. When contractility becomes impaired and the ventricle dilates, the afterload rises and limits output. This may start a vicious circle, in which cardiac output is reduced as oxygen requirements are increased.
Numerology
Chaldean Numerology
The numerical value of afterload in Chaldean Numerology is: 8
Pythagorean Numerology
The numerical value of afterload in Pythagorean Numerology is: 1
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Translations for afterload
From our Multilingual Translation Dictionary
- μεταφόρτωσηGreek
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"afterload." Definitions.net. STANDS4 LLC, 2024. Web. 6 May 2024. <https://www.definitions.net/definition/afterload>.
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