MPP+, the active metabolite of MPTP.
A neurotoxin which cannot cross the blood brain barrier, but once in contact it can destroy the dopaminergic neurons of the substantia nigra.
U.S. National Library of Medicine
An active neurotoxic metabolite of 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE. The compound reduces dopamine levels, inhibits the biosynthesis of catecholamines, depletes cardiac norepinephrine and inactivates tyrosine hydroxylase. These and other toxic effects lead to cessation of oxidative phosphorylation, ATP depletion, and cell death. The compound, which is related to PARAQUAT, has also been used as an herbicide.
The numerical value of 1-methyl-4-phenylpyridinium in Chaldean Numerology is: 1
The numerical value of 1-methyl-4-phenylpyridinium in Pythagorean Numerology is: 4
Images & Illustrations of 1-methyl-4-phenylpyridinium
Find a translation for the 1-methyl-4-phenylpyridinium definition in other languages:
Select another language:
Discuss these 1-methyl-4-phenylpyridinium definitions with the community:
Word of the Day
Would you like us to send you a FREE new word definition delivered to your inbox daily?
Use the citation below to add this definition to your bibliography:
"1-methyl-4-phenylpyridinium." Definitions.net. STANDS4 LLC, 2017. Web. 24 Jul 2017. <http://www.definitions.net/definition/1-methyl-4-phenylpyridinium>.