tricyclic, tricyclic antidepressant, tricyclic antidepressant drug(noun)
an antidepressant drug that acts by blocking the reuptake of norepinephrine and serotonin and thus making more of those substances available to act on receptors in the brain
Tricyclic antidepressants are heterocyclic chemical compounds used primarily as antidepressants. The TCAs were first discovered in the early 1950s and were subsequently introduced later in the decade; they are named after their chemical structure, which contains three rings of atoms. The tetracyclic antidepressants, which contain four rings of atoms, are a closely related group of antidepressant compounds. In recent times, the TCAs have been largely replaced in clinical use in most parts of the world by newer antidepressants such as the selective serotonin reuptake inhibitors, serotonin-norepinephrine reuptake inhibitors and the norepinephrine reuptake inhibitors like reboxetine which typically have more favorable side-effects profiles, though they are still sometimes prescribed for certain indications.
The numerical value of tricyclic antidepressant in Chaldean Numerology is: 9
The numerical value of tricyclic antidepressant in Pythagorean Numerology is: 6
Images & Illustrations of tricyclic antidepressant
Find a translation for the tricyclic antidepressant definition in other languages:
Select another language:
Discuss these tricyclic antidepressant definitions with the community:
Word of the Day
Would you like us to send you a FREE new word definition delivered to your inbox daily?
Use the citation below to add this definition to your bibliography:
"tricyclic antidepressant." Definitions.net. STANDS4 LLC, 2018. Web. 20 Mar. 2018. <https://www.definitions.net/definition/tricyclic antidepressant>.