What does platelet-derived growth factor mean?
Definitions for platelet-derived growth factor
platelet-derived growth fac·tor
This dictionary definitions page includes all the possible meanings, example usage and translations of the word platelet-derived growth factor.
Wikidata
Platelet-derived growth factor
In molecular biology, platelet-derived growth factor is one of the numerous growth factors, or proteins that regulate cell growth and division. In particular, it plays a significant role in blood vessel formation, the growth of blood vessels from already-existing blood vessel tissue. Uncontrolled angiogenesis is a characteristic of cancer. In chemical terms, platelet-derived growth factor is dimeric glycoprotein composed of two A or two B chains or a combination of the two. PDGF is a potent mitogen for cells of mesenchymal origin, including smooth muscle cells and glial cells. In both mouse and human, the PDGF signalling network consists of four ligands, PDGFA-D, and two receptors, PDGFRalpha and PDGFRbeta. All PDGFs function as secreted, disulphide-linked homodimers, but only PDGFA and B can form functional heterodimers. Though it is synthesized stored and released by platelets upon activation, it is produced by a plethora of cells including smooth muscle cells, activated macrophages, and endothelial cells
U.S. National Library of Medicine
Platelet-Derived Growth Factor
Mitogenic peptide growth hormone carried in the alpha-granules of platelets. It is released when platelets adhere to traumatized tissues. Connective tissue cells near the traumatized region respond by initiating the process of replication.
Numerology
Chaldean Numerology
The numerical value of platelet-derived growth factor in Chaldean Numerology is: 4
Pythagorean Numerology
The numerical value of platelet-derived growth factor in Pythagorean Numerology is: 6
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"platelet-derived growth factor." Definitions.net. STANDS4 LLC, 2024. Web. 11 May 2024. <https://www.definitions.net/definition/platelet-derived+growth+factor>.
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