U.S. National Library of Medicine
NFATC Transcription Factors
A family of transcription factors characterized by the presence of highly conserved calcineurin- and DNA-binding domains. NFAT proteins are activated in the CYTOPLASM by the calcium-dependent phosphatase CALCINEURIN. They transduce calcium signals to the nucleus where they can interact with TRANSCRIPTION FACTOR AP-1 or NF-KAPPA B and initiate GENETIC TRANSCRIPTION of GENES involved in CELL DIFFERENTIATION and development. NFAT proteins stimulate T-CELL activation through the induction of IMMEDIATE-EARLY GENES such as INTERLEUKIN-2.
The numerical value of nfatc transcription factors in Chaldean Numerology is: 5
The numerical value of nfatc transcription factors in Pythagorean Numerology is: 5
Images & Illustrations of nfatc transcription factors
Find a translation for the nfatc transcription factors definition in other languages:
Select another language:
Discuss these nfatc transcription factors definitions with the community:
Word of the Day
Would you like us to send you a FREE new word definition delivered to your inbox daily?
Use the citation below to add this definition to your bibliography:
"nfatc transcription factors." Definitions.net. STANDS4 LLC, 2018. Web. 25 Feb. 2018. <https://www.definitions.net/definition/nfatc transcription factors>.