Definitions for marfan's syndrome
mar·fan's syn·drome

Princeton's WordNetRate this definition:0.0 / 0 votes

1. Marfan's syndromenoun

   an autosomal dominant disease characterized by elongated bones (especially of limbs and digits) and abnormalities of the eyes and circulatory system

WikipediaRate this definition:0.0 / 0 votes

1. marfan's syndrome

   Marfan syndrome (MFS) is a multi-systemic genetic disorder that affects the connective tissue. Those with the condition tend to be tall and thin, with long arms, legs, fingers, and toes. They also typically have exceptionally flexible joints and abnormally curved spines. The most serious complications involve the heart and aorta, with an increased risk of mitral valve prolapse and aortic aneurysm. The lungs, eyes, bones, and the covering of the spinal cord are also commonly affected. The severity of the symptoms is variable.MFS is caused by a mutation in FBN1, one of the genes that makes fibrillin, which results in abnormal connective tissue. It is an autosomal dominant disorder. In about 75% of cases, it is inherited from a parent with the condition, while in about 25% it is a new mutation. Diagnosis is often based on the Ghent criteria.There is no known cure for MFS. Many of those with the disorder have a normal life expectancy with proper treatment. Management often includes the use of beta blockers such as propranolol or atenolol or, if they are not tolerated, calcium channel blockers or ACE inhibitors. Surgery may be required to repair the aorta or replace a heart valve. Avoiding strenuous exercise is recommended for those with the condition.About 1 in 5,000 to 1 in 10,000 people have MFS. Rates of the condition are similar in different regions of the world. It is named after French pediatrician Antoine Marfan, who first described it in 1896.

ChatGPTRate this definition:0.0 / 0 votes

1. marfan's syndrome

   Marfan's Syndrome is a genetic disorder that affects the body's connective tissue, the tissue that holds all the body's cells, organs, and tissue together and helps the body grow and develop properly. This syndrome most often affects the heart, eyes, blood vessels, and skeleton, leading to various physical complications. Symptoms vary widely, but might include tall height, slender body, disproportionately long arms, legs, and fingers, heart defects, eye conditions among others. It is caused by a defect in a gene called FBN1.

Matched Categories

1. • Autosomal Dominant Disease

How to pronounce marfan's syndrome?

1. Alex

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How to say marfan's syndrome in sign language?

Numerology

1. Chaldean Numerology

   The numerical value of marfan's syndrome in Chaldean Numerology is: 1

2. Pythagorean Numerology

   The numerical value of marfan's syndrome in Pythagorean Numerology is: 5

References

1. ^ Princeton's WordNet
   http://wordnetweb.princeton.edu/perl/webwn?s=marfan's syndrome
2. ^ Wikipedia
   https://en.wikipedia.org/wiki/Marfan'S_Syndrome
3. ^ ChatGPT
   https://chat.openai.com