What does complement c1 inhibitor protein mean?
Definitions for complement c1 inhibitor protein
com·ple·ment c1 in·hibitor pro·tein
This dictionary definitions page includes all the possible meanings, example usage and translations of the word complement c1 inhibitor protein.
Wikipedia
complement c1 inhibitor protein
C1-inhibitor (C1-inh, C1 esterase inhibitor) is a protease inhibitor belonging to the serpin superfamily. Its main function is the inhibition of the complement system to prevent spontaneous activation but also as the major regulator of the contact system. C1-inhibitor is an acute-phase protein that circulates in blood at levels of around 0.25 g/L. The levels rise ~2-fold during inflammation. C1-inhibitor irreversibly binds to and inactivates C1r and C1s proteases in the C1 complex of classical pathway of complement. MASP-1 and MASP-2 proteases in MBL complexes of the lectin pathway are also inactivated. This way, C1-inhibitor prevents the proteolytic cleavage of later complement components C4 and C2 by C1 and MBL. Although named after its complement inhibitory activity, C1-inhibitor also inhibits proteases of the fibrinolytic, clotting, and kinin pathways. Note that C1-inhibitor is the most important physiological inhibitor of plasma kallikrein, fXIa, and fXIIa.
U.S. National Library of Medicine
Complement C1 Inhibitor Protein
An endogenous 105-kDa plasma glycoprotein produced primarily by the LIVER and MONOCYTES. It inhibits a broad spectrum of proteases, including the COMPLEMENT C1R and the COMPLEMENT C1S proteases of the CLASSICAL COMPLEMENT PATHWAY, and the MANNOSE-BINDING PROTEIN-ASSOCIATED SERINE PROTEASES. C1-INH-deficient individuals suffer from HEREDITARY ANGIOEDEMA TYPES I AND II.
Numerology
Chaldean Numerology
The numerical value of complement c1 inhibitor protein in Chaldean Numerology is: 3
Pythagorean Numerology
The numerical value of complement c1 inhibitor protein in Pythagorean Numerology is: 5
Translations for complement c1 inhibitor protein
From our Multilingual Translation Dictionary
- Ингибитор комплемента c1Russian
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"complement c1 inhibitor protein." Definitions.net. STANDS4 LLC, 2024. Web. 15 Jun 2024. <https://www.definitions.net/definition/complement+c1+inhibitor+protein>.
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