What does bromopyruvic acid mean?
Definitions for bromopyruvic acid
bro·mopy·ru·vic acid
This dictionary definitions page includes all the possible meanings, example usage and translations of the word bromopyruvic acid.
Wiktionary
bromopyruvic acidnoun
A synthetic brominated derivative of pyruvic acid with potential applications in cancer treatment.
Wikidata
Bromopyruvic acid
Bromopyruvic acid, or bromopyruvate, is a synthetic brominated derivative of pyruvic acid. It is being studied as a potential treatment for certain types of cancer. Initial studies in laboratory animals researchers at Johns Hopkins showed that bromopyruvic acid is effective at eliminating aggressive liver tumors. According to the Warburg hypothesis, unlike normal tissues, which derive most of their energy in the form of adenosine triphosphate by metabolizing either glucose or fatty acids for energy production in the mitochondria, aggressive cancers obtain much of their ATP by metabolizing glucose directly to lactic acid. The mechanism of action of bromopyruvic acid involves interruption of this latter process by the inhibition of the enzyme Glyceraldehyde 3-phosphate-dehydrogenase. The research group of J.F. Geschwind reported that intra-arterial delivery of bromopyruvic acid directly to the site of a tumor represents a new strategy for stopping the growth of liver cancer while minimizing toxic side-effects. While pre-clinical studies have been promising, human clinical trials to study the effectiveness of bromopyruvic acid have not yet begun. Application for patent has already been submitted.
Numerology
Chaldean Numerology
The numerical value of bromopyruvic acid in Chaldean Numerology is: 4
Pythagorean Numerology
The numerical value of bromopyruvic acid in Pythagorean Numerology is: 5
Translations for bromopyruvic acid
From our Multilingual Translation Dictionary
- бромпировиноградной кислотыRussian
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"bromopyruvic acid." Definitions.net. STANDS4 LLC, 2024. Web. 28 Apr. 2024. <https://www.definitions.net/definition/bromopyruvic+acid>.
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