Definitions for booster dose
boost·er dose

Princeton's WordNetRate this definition:0.0 / 0 votes

1. booster, booster dose, booster shot, recall dosenoun

   an additional dose that makes sure the first dose was effective

WiktionaryRate this definition:0.0 / 0 votes

1. booster dosenoun

   A dose of an antigen designed to strengthen immunity after an earlier immunizing dose.

WikipediaRate this definition:0.0 / 0 votes

1. Booster dose

   A booster dose is an extra administration of a vaccine after an earlier (primer) dose. After initial immunization, a booster provides a re-exposure to the immunizing antigen. It is intended to increase immunity against that antigen back to protective levels after memory against that antigen has declined through time. For example, tetanus shot boosters are often recommended every 10 years, by which point memory cells specific against tetanus lose their function or undergo apoptosis.The need for a booster dose following a primary vaccination is evaluated in several ways. One way is to measure the level of antibodies specific against a disease a few years after the primary dose is given. Anamnestic response, the rapid production of antibodies after a stimulus of an antigen, is a typical way to measure the need for a booster dose of a certain vaccine. If the anamnestic response is high after receiving a primary vaccine many years ago, there is most likely little to no need for a booster dose. People can also measure the active B and T cell activity against that antigen after a certain amount of time that the primary vaccine was administered or determine the prevalence of the disease in vaccinated populations.If a patient receives a booster dose but already has a high level of antibody, then a reaction called an Arthus reaction could develop, a localized form of Type III hypersensitivity induced by high levels of IgG antibodies causing inflammation. The inflammation is often self-resolved over the course of a few days but could be avoided altogether by increasing the length of time between the primary vaccine and the booster dose.It is not yet fully clear why some vaccines such as hepatitis A and B are effective for life, and some such as tetanus need boosters. The prevailing theory is that if the immune system responds to a primary vaccine rapidly, the body does not have time to sufficiently develop immunological memory against the disease, and memory cells will not persist in high numbers for the lifetime of the human. After a primary response of the immune system against a vaccination, memory T helper cells and B cells persist at a fairly constant level in germinal centers, undergoing cell division at a slow to nonexistent rate. While these cells are long-lived, they do not typically undergo mitosis, and eventually, the rate of loss of these cells will be greater than the rate of gain. In these cases, a booster dose is required to "boost" the memory B and T cell count back up again.

WikidataRate this definition:0.0 / 0 votes

1. Booster dose

   In medicine, a booster dose is an extra administration of a vaccine after an earlier dose. After initial immunization, a booster injection or booster dose is a re-exposure to the immunizing antigen cell. It is intended to increase immunity against that antigen back to protective levels after it has been shown to have decreased or after a specified period. For example, tetanus shot boosters are often recommended every 10 years. If a patient receives a booster dose this is a good thing but already has a high level of antibody, then a reaction called an Arthus reaction could develop, a localized form of Type III hypersensitivity, induced by fixation of complement by preformed circulating antibodies. In severe cases, the degree of complement fixation can be so substantial that it induces local tissue necrosis.

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How to pronounce booster dose?

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How to say booster dose in sign language?

Numerology

1. Chaldean Numerology

   The numerical value of booster dose in Chaldean Numerology is: 4

2. Pythagorean Numerology

   The numerical value of booster dose in Pythagorean Numerology is: 2

Examples of booster dose in a Sentence

1. Paul Burton:

   We're going to have to wait for a couple of months yet, until we can see how those data develop and mature to understand when will that additional booster dose -- if needed -- have to be given, i think we can be confident, Wolf, getting a booster shot will provide protection throughout the holiday season and throughout these winter months.

2. Helen Keipp Talbot:

   And I really feel like yes we may move the needle a little bit by giving a booster dose, but the real fact of the matter is this is a pandemic of the unvaccinated.

3. Michael Osterholm:

   These are really about finishing a primary series. Think about childhood immunizations. We have vaccines for which we need three of four doses. What we found here is that the immune-compromised often didn't mount an adequate response at all. So we're still trying to build that. That is different than a booster dose where someone did respond and in fact over time that wanes, i think it was a great decision.

4. Paul Offit:

   I think we need to show why a booster dose is clearly of benefit to 18-29 year-olds, because if it's not clearly of benefit, we have to consider the fact that myocarditis was a second dose phenomenon and may also be a third dose phenomenon. Do the benefits clearly and definitively outweigh risks for 18-29 year old ?

5. Peter Marks:

   I think we're very much on board with the idea that we simply can't be boosting people as frequently as we are, and I'm the first to acknowledge that this additional fourth booster dose that was authorized was a stopgap measure until we got things in place for the next potential booster, given the emerging data, it was done because of the amount of harm that has come to our older population in the United States with 1 in 100 individuals over the age 65 having died in the past two years of Covid-19, so we need to protect that population.

References

1. ^ Princeton's WordNet
   http://wordnetweb.princeton.edu/perl/webwn?s=booster dose
2. ^ Wiktionary
   https://en.wiktionary.org/wiki/Booster_Dose
3. ^ Wikipedia
   https://en.wikipedia.org/wiki/Booster_Dose
4. ^ Wikidata
   https://www.wikidata.org/w/index.php?search=booster dose