Definitions for addison's disease
ad·di·son's dis·ease

Princeton's WordNetRate this definition:0.0 / 0 votes

1. Addison's disease, Addison's syndrome, hypoadrenalism, hypoadrenocorticismnoun

   a glandular disorder caused by failure of function of the cortex of the adrenal gland and marked by anemia and prostration with brownish skin

WikipediaRate this definition:0.0 / 0 votes

1. Addison's disease

   Addison's disease, also known as primary adrenal insufficiency, is a rare long-term endocrine disorder characterized by inadequate production of the steroid hormones cortisol and aldosterone by the two outer layers of the cells of the adrenal glands (adrenal cortex), causing adrenal insufficiency. Symptoms generally come on slowly and insidiously and may include abdominal pain and gastrointestinal abnormalities, weakness, and weight loss. Darkening of the skin in certain areas may also occur. Under certain circumstances, an adrenal crisis may occur with low blood pressure, vomiting, lower back pain, and loss of consciousness. Mood changes may also occur. Rapid onset of symptoms indicates acute adrenal failure, which is a clinical emergency. An adrenal crisis can be triggered by stress, such as from an injury, surgery, or infection.Addison's disease arises from problems with the adrenal gland such that not enough of the steroid hormone cortisol and possibly aldosterone are produced. It is an autoimmune disease which affects some genetically predisposed people in whom the body's own immune system has started to target the adrenal gland. While it can follow tuberculosis, in many adult cases it is unclear what has triggered onset of the disease. Causes can include certain medications, sepsis, and bleeding into both adrenal glands. Addison's disease is generally diagnosed by blood tests, urine tests, and medical imaging (adrenal crises can occur in all forms of adrenal insufficiency)Treatment involves replacing the absent hormones. This involves taking a synthetic corticosteroid, such as hydrocortisone or fludrocortisone. These medications are usually taken by mouth. Lifelong, continuous steroid replacement therapy is required, with regular follow-up treatment and monitoring for other health problems. A high-salt diet may also be useful in some people. If symptoms worsen, an injection of corticosteroid is recommended (people need to carry a dose with them). Often, large amounts of intravenous fluids with the sugar dextrose are also required. With appropriate treatment, long-term outcomes are typically favorable, and most people are able to lead a reasonably normal life. Without treatment, an adrenal crisis can result in death.Addison's disease affects about 9 to 14 per 100,000 people in the developed world. It occurs most frequently in middle-aged females. Secondary adrenal insufficiency is more prevalent. The disease is named after Thomas Addison, a graduate of the University of Edinburgh Medical School, who first described the condition in 1855 (the adjective "addisonian" is sometimes also used).

ChatGPTRate this definition:0.0 / 0 votes

1. addison's disease

   Addison's disease is a rare and chronic disorder of the adrenal glands wherein the glands do not produce sufficient amounts of certain hormones, such as cortisol and aldosterone. This disease is also referred to as primary adrenal insufficiency. Symptoms include fatigue, muscle weakness, loss of appetite, weight loss, and darkening of the skin. It can be life threatening, and it typically requires ongoing treatment with replacement steroids. It can affect people of all ages, though it is most common in people between 30 and 50 years old.

Webster DictionaryRate this definition:0.0 / 0 votes

1. Addison's disease

   a morbid condition causing a peculiar brownish discoloration of the skin, and thought, at one time, to be due to disease of the suprarenal capsules (two flat triangular bodies covering the upper part of the kidneys), but now known not to be dependent upon this causes exclusively. It is usually fatal

2. Etymology: [Named from Thomas Addison, M. D., of London, who first described it.]

WikidataRate this definition:0.0 / 0 votes

1. Addison's disease

   Addison’s disease is a rare, chronic endocrine disorder in which the adrenal glands do not produce sufficient steroid hormones. It is characterised by a number of relatively nonspecific symptoms, such as abdominal pain and weakness, but under certain circumstances, these may progress to Addisonian crisis, a severe illness which may include very low blood pressure and coma. The condition arises from problems with the adrenal gland, "primary adrenal insufficiency", and can be caused by damage by the body's own immune system, certain infections, or various rarer causes. Addison's disease is also known as chronic primary adrenocortical insufficiency, to distinguish it from acute primary adrenocortical insufficiency, most often caused by Waterhouse-Friderichsen syndrome. Addison's disease should also be distinguished from secondary and tertiary adrenal insufficiency, which are caused by deficiency of ACTH and CRH, respectively. Despite this distinction, Addisonian crises can happen in all forms of adrenal insufficiency.

Matched Categories

1. • Glandular Disease

How to pronounce addison's disease?

1. Alex

   US English

   David

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   Mark

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   Daniel

   British

   Libby

   British

   Mia

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   Karen

   Australian

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   Australian

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   Priya

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   Neerja

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   Zira

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   Oliver

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   Wendy

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How to say addison's disease in sign language?

Numerology

1. Chaldean Numerology

   The numerical value of addison's disease in Chaldean Numerology is: 5

2. Pythagorean Numerology

   The numerical value of addison's disease in Pythagorean Numerology is: 3

Examples of addison's disease in a Sentence

1. Sheryl Craig:

   I've heard some very convincing presentations by doctors for the Addison's disease theory, so, when asked, I always say that it was probably Addison's disease.

References

1. ^ Princeton's WordNet
   http://wordnetweb.princeton.edu/perl/webwn?s=addison's disease
2. ^ Wikipedia
   https://en.wikipedia.org/wiki/Addison'S_Disease
3. ^ ChatGPT
   https://chat.openai.com
4. ^ Webster Dictionary
   https://www.merriam-webster.com/dictionary/addison's disease
5. ^ Wikidata
   https://www.wikidata.org/w/index.php?search=addison's disease