What does Glutamate Dehydrogenase mean?
Definitions for Glutamate Dehydrogenase
glu·ta·mate dehy·dro·ge·nase
This dictionary definitions page includes all the possible meanings, example usage and translations of the word Glutamate Dehydrogenase.
Wikidata
Glutamate dehydrogenase
Glutamate dehydrogenase is an enzyme, present in most microbes and the mitochondria of eukaryotes, as are some of the other enzymes required for urea synthesis, that converts glutamate to α-ketoglutarate, and vice versa. In animals, the produced ammonia is usually used as a substrate in the urea cycle. Typically, the α-ketoglutarate to glutamate reaction does not occur in mammals as glutamate dehydrogenase equilibrium favours the production of ammonia and α-ketoglutarate. Glutamate dehydrogenase also has a very low affinity for ammonia, and therefore toxic levels of ammonia would have to be present in the body for the reverse reaction to proceed. In bacteria, the ammonia is assimilated to amino acids via glutamate and aminotransferases. In plants, the enzyme can work in either direction depending on environment and stress. Transgenic plants expressing microbial GLDHs are improved in tolerance to herbicide, water deficit, and pathogen infections. They are more nutritionally valuable. ⁕ Glutamate ⁕ α-Ketoglutarate The enzyme represents a key link between catabolic and metabolic pathways, and is, therefore, ubiquitous in eukaryotes.
U.S. National Library of Medicine
Glutamate Dehydrogenase
An enzyme that catalyzes the conversion of L-glutamate and water to 2-oxoglutarate and NH3 in the presence of NAD+. (From Enzyme Nomenclature, 1992) EC 1.4.1.2.
Numerology
Chaldean Numerology
The numerical value of Glutamate Dehydrogenase in Chaldean Numerology is: 9
Pythagorean Numerology
The numerical value of Glutamate Dehydrogenase in Pythagorean Numerology is: 5
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"Glutamate Dehydrogenase." Definitions.net. STANDS4 LLC, 2024. Web. 26 Apr. 2024. <https://www.definitions.net/definition/Glutamate+Dehydrogenase>.
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