What does Dopamine Reuptake Inhibitor mean?
Definitions for Dopamine Reuptake Inhibitor
dopamine re·up·take in·hibitor
This dictionary definitions page includes all the possible meanings, example usage and translations of the word Dopamine Reuptake Inhibitor.
Wikipedia
Dopamine reuptake inhibitor
A dopamine reuptake inhibitor (DRI) is a class of drug which acts as a reuptake inhibitor of the monoamine neurotransmitter dopamine by blocking the action of the dopamine transporter (DAT). Reuptake inhibition is achieved when extracellular dopamine not absorbed by the postsynaptic neuron is blocked from re-entering the presynaptic neuron. This results in increased extracellular concentrations of dopamine and increase in dopaminergic neurotransmission.DRIs are used in the treatment of attention-deficit hyperactivity disorder (ADHD) and narcolepsy for their psychostimulant effects, and in the treatment of obesity and binge eating disorder for their appetite suppressant effects. They are sometimes used as antidepressants in the treatment of mood disorders, but their use as antidepressants is limited given that strong DRIs have a high abuse potential and legal restrictions on their use. Lack of dopamine reuptake and the increase in extracellular levels of dopamine have been linked to increased susceptibility to addictive behavior given increase in dopaminergic neurotransmission. The dopaminergic pathways are considered to be strong reward centers. Many DRIs such as cocaine are drugs of abuse due to the rewarding effects evoked by elevated synaptic concentrations of dopamine in the brain.
Numerology
Chaldean Numerology
The numerical value of Dopamine Reuptake Inhibitor in Chaldean Numerology is: 6
Pythagorean Numerology
The numerical value of Dopamine Reuptake Inhibitor in Pythagorean Numerology is: 8
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"Dopamine Reuptake Inhibitor." Definitions.net. STANDS4 LLC, 2024. Web. 28 Apr. 2024. <https://www.definitions.net/definition/Dopamine+Reuptake+Inhibitor>.
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