What does Churg-Strauss syndrome mean?

Definitions for Churg-Strauss syndrome
churg-strauss syn·drome

This dictionary definitions page includes all the possible meanings, example usage and translations of the word Churg-Strauss syndrome.


  1. churg-strauss syndrome

    Eosinophilic granulomatosis with polyangiitis (EGPA), formerly known as allergic granulomatosis, is an extremely rare autoimmune condition that causes inflammation of small and medium-sized blood vessels (vasculitis) in persons with a history of airway allergic hypersensitivity (atopy).It usually manifests in three stages. The early (prodromal) stage is marked by airway inflammation; almost all patients experience asthma and/or allergic rhinitis. The second stage is characterized by abnormally high numbers of eosinophils (hypereosinophilia), which causes tissue damage, most commonly to the lungs and the digestive tract. The third stage consists of vasculitis, which can eventually lead to cell death and can be life-threatening.This condition is now called "eosinophilic granulomatosis with polyangiitis" to remove all eponyms from the vasculitides. To facilitate the transition, it was referred to as "eosinophilic granulomatosis with polyangiitis (Churg–Strauss)" for a period of time starting in 2012. Prior to this it was known as "Churg–Strauss syndrome", named after Jacob Churg and Lotte Strauss, who first published about the syndrome in 1951 using the term allergic granulomatosis to describe it. It is a type of systemic necrotizing vasculitis. Effective treatment of EGPA requires suppression of the immune system with medication. This is typically glucocorticoids, followed by other agents such as cyclophosphamide or azathioprine.


  1. Churg-Strauss syndrome

    Churg–Strauss syndrome is a medium and small vessel autoimmune vasculitis, leading to necrosis. It involves mainly the blood vessels of the lungs, gastrointestinal system, and peripheral nerves, but also affects the heart, skin, and kidneys. It is a rare disease that is non-inheritable and non-transmissible. Churg–Strauss syndrome was once considered a type of polyarteritis nodosa due to their similar morphologies. The syndrome was first described by Drs. Jacob Churg and Lotte Strauss at Mount Sinai Hospital in New York City in 1951.

U.S. National Library of Medicine

  1. Churg-Strauss Syndrome

    Widespread necrotizing angiitis with granulomas. Pulmonary involvement is frequent. Asthma or other respiratory infection may precede evidence of vasculitis. Eosinophilia and lung involvement differentiate this disease from POLYARTERITIS NODOSA.

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  1. Chaldean Numerology

    The numerical value of Churg-Strauss syndrome in Chaldean Numerology is: 9

  2. Pythagorean Numerology

    The numerical value of Churg-Strauss syndrome in Pythagorean Numerology is: 8


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