What does zona reticularis mean?
Definitions for zona reticularis
zona retic·u·laris
This dictionary definitions page includes all the possible meanings, example usage and translations of the word zona reticularis.
Wiktionary
zona reticularisnoun
The innermost layer of the adrenal cortex, responsible for the production of precursor androgens including dehydroepiandrosterone and androstenedione from cholesterol.
Wikipedia
Zona reticularis
The zona reticularis (sometimes, reticulate zone) is the innermost layer of the adrenal cortex, lying deep to the zona fasciculata and superficial to the adrenal medulla. The cells are arranged cords that project in different directions giving a net-like appearance (L. reticulum - net).Cells in the zona reticularis produce precursor androgens including dehydroepiandrosterone (DHEA) and androstenedione from cholesterol. DHEA is further converted to DHEA-sulfate via a sulfotransferase, SULT2A1. These precursors are not further converted in the adrenal cortex if the cells lack 17β-Hydroxysteroid dehydrogenase. Instead, they are released into the blood stream and taken up in the testis and ovaries to produce testosterone and the estrogens respectively. ACTH partially regulates adrenal androgen secretion, also CRH.In humans the reticularis layer does contain 17α-hydroxylase; this hydroxylates pregnenolone, which is then converted to cortisol by a mixed function oxidase. In rodents, the lack of 17α-hydroxylase results in the synthesis of corticosterone instead of cortisol as in the human.
Wikidata
Zona reticularis
The zona reticularis is the innermost layer of the adrenal cortex, lying deep to the zona fasciculata and superficial to the adrenal medulla. The cells are arranged cords that project in different directions giving a net-like appearance. Cells in the zona reticularis produce precursor androgens including dehydroepiandrosterone and androstenedione from cholesterol. DHEA is further converted to DHEA-sulfate via a sulfotransferase, SULT2A1. These precursors are not further converted in the adrenal cortex if the cells lack 17Beta Hydroxysteroid dehydrogenase. Instead, they are released into the blood stream and taken up in the testis and ovaries to produce testosterone and the estrogens respectively. ACTH partially regulates adrenal androgen secretion, also CRH. In humans the reticularis layer does contain 17 alpha-hydroxylase; this hydroxylates pregnenolone, which is then converted to cortisol by a mixed function oxidase. In rodents, the lack of 17alpha-hydroxylase results in the synthesis of corticosterone instead of cortisol as in the human.
U.S. National Library of Medicine
Zona Reticularis
The inner zone of the adrenal cortex. This zone produces the enzymes that convert PREGNENOLONE, a 21-carbon steroid, to 19-carbon steroids (DEHYDROEPIANDROSTERONE; and ANDROSTENEDIONE) via 17-ALPHA-HYDROXYPREGNENOLONE.
Numerology
Chaldean Numerology
The numerical value of zona reticularis in Chaldean Numerology is: 6
Pythagorean Numerology
The numerical value of zona reticularis in Pythagorean Numerology is: 2
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"zona reticularis." Definitions.net. STANDS4 LLC, 2024. Web. 1 May 2024. <https://www.definitions.net/definition/zona+reticularis>.
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