Definitions for zak

This page provides all possible meanings and translations of the word zak


  1. zak(Noun)


  2. zak(Noun)

    Sixpence or a "small amount of money".

  3. Zak(ProperNoun)

    A male given name, diminutive of Zachariah and Zachary.


  1. ZAK

    Sterile alpha motif and leucine zipper containing kinase AZK, also known as ZAK, is a human gene. This gene is a member of the MAPKKK family of signal transduction molecules and encodes a protein with an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif. This magnesium-binding protein forms homodimers and is located in the cytoplasm. The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells. The protein also has pro-apoptotic activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

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