U.S. National Library of Medicine
Unfolded Protein Response
A cellular response to environmental insults that cause disruptions in PROTEIN FOLDING and/or accumulation of defectively folded protein in the ENDOPLASMIC RETICULUM. It consists of a group of regulatory cascades that are triggered as a response to altered levels of calcium and/or the redox state of the endoplasmic reticulum. Persistent activation of the unfolded protein response leads to the induction of APOPTOSIS.
The numerical value of unfolded protein response in Chaldean Numerology is: 4
The numerical value of unfolded protein response in Pythagorean Numerology is: 1
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"unfolded protein response." Definitions.net. STANDS4 LLC, 2017. Web. 29 Mar. 2017. <http://www.definitions.net/definition/unfolded protein response>.