Definitions for unfolded protein response
This page provides all possible meanings and translations of the word unfolded protein response
U.S. National Library of Medicine
Unfolded Protein Response
A cellular response to environmental insults that cause disruptions in PROTEIN FOLDING and/or accumulation of defectively folded protein in the ENDOPLASMIC RETICULUM. It consists of a group of regulatory cascades that are triggered as a response to altered levels of calcium and/or the redox state of the endoplasmic reticulum. Persistent activation of the unfolded protein response leads to the induction of APOPTOSIS.
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"unfolded protein response." Definitions.net. STANDS4 LLC, 2014. Web. 22 Nov. 2014. <http://www.definitions.net/definition/unfolded protein response>.