Definitions for tyrocidine

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Princeton's WordNetRate this definition:(0.00 / 0 votes)

  1. tyrocidine, tyrocidin(noun)

    a basic polypeptide antibiotic derived from a soil bacterium; a major component of tyrothricin

WiktionaryRate this definition:(0.00 / 0 votes)

  1. tyrocidine(Noun)

    a polypeptide antibiotic produced by bacteria in the soil

FreebaseRate this definition:(0.00 / 0 votes)

  1. Tyrocidine

    Tyrocidine is a mixture of cyclic decapeptides produced by the bacteria Bacillus brevis found in soil. It can be composed of 4 different amino acid sequences, giving tyrocidine A–D. Tyrocidine is the major constituent of tyrothricin, which also contains gramicidin. Tyrocidine was the first commercially available antibiotic, but has been found to be toxic toward human blood and reproductive cells. The function of tyrocidine within its host B. brevis is thought to be regulation of sporulation. Tyrocidines A, B, and C are cyclic decapeptides. The biosynthesis of tyrocidine involves three enzymes. Parts of its sequence are identical to gramicidin S.

U.S. National Library of MedicineRate this definition:(0.00 / 0 votes)

  1. Tyrocidine

    An antibiotic mixture produced by Bacillus brevis which may be separated into three components, tyrocidines A, B, and C. It is the major constituent (40-60 per cent) of tyrothricin, gramicidin accounting for the remaining 10-20 per cent active material. It is a topical antimicrobial agent, that is very toxic parenterally.

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