Definitions for tioguanine
This page provides all possible meanings and translations of the word tioguanine
A particular drug used to treat cancer.
Tioguanine, formerly thioguanine, also commonly referred to as 6-thioguanine; the trade name is Lanvis. 6-TG belongs to the thiopurine family of drugs that also include mercaptopurine and azathioprine, which are examples of antimetabolites. It is a purine analogue of the nucleobase guanine. Its drug usage was originally as a cytostatic agent in chemotherapy for the treatment of acute lymphoblasic leukemia in children, but has been used less frequently in recent years because of safety concerns. However, it is becoming more widely used for treating ulcerative colitis, a form of inflammatory bowel disease, and some autoimmune diseases. It is a pale yellow, odorless, crystalline powder.
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