Definitions for tachyphylaxis
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Wiktionary
tachyphylaxis(Noun)
A rapidly decreasing response to a drug following administration of the initial doses
U.S. National Library of Medicine
Tachyphylaxis
Rapidly decreasing response to a drug or physiologically active agent after administration of a few doses. In immunology, it is the rapid immunization against the effect of toxic doses of an extract or serum by previous injection of small doses. (Dorland, 28th ed)
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"tachyphylaxis." Definitions.net. STANDS4 LLC, 2013. Web. 19 Jun 2013. <http://www.definitions.net/definition/tachyphylaxis>.

