What does t-cell receptor mean?

Definitions for t-cell receptor
t-cell recep·tor

This dictionary definitions page includes all the possible meanings, example usage and translations of the word t-cell receptor.

Wikipedia

  1. T-cell receptor

    The T-cell receptor, or TCR, is a molecule found on the surface of T cells, or T lymphocytes, that is responsible for recognizing fragments of antigen as peptides bound to major histocompatibility complex (MHC) molecules. The binding between TCR and antigen peptides is of relatively low affinity and is degenerate: that is, many TCRs recognize the same antigen peptide and many antigen peptides are recognized by the same TCR.The TCR is composed of two different protein chains (that is, it is a heterodimer). In humans, in 95% of T cells the TCR consists of an alpha (α) chain and a beta (β) chain (encoded by TRA and TRB, respectively), whereas in 5% of T cells the TCR consists of gamma and delta (γ/δ) chains (encoded by TRG and TRD, respectively). This ratio changes during ontogeny and in diseased states (such as leukemia). It also differs between species. Orthologues of the 4 loci have been mapped in various species. Each locus can produce a variety of polypeptides with constant and variable regions.When the TCR engages with antigenic peptide and MHC (peptide/MHC), the T lymphocyte is activated through signal transduction, that is, a series of biochemical events mediated by associated enzymes, co-receptors, specialized adaptor molecules, and activated or released transcription factors.

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Numerology

  1. Chaldean Numerology

    The numerical value of t-cell receptor in Chaldean Numerology is: 9

  2. Pythagorean Numerology

    The numerical value of t-cell receptor in Pythagorean Numerology is: 8

Examples of t-cell receptor in a Sentence

  1. Ripley Ballou:

    Viruses are pretty simple organisms and they all have antigens on their surface that are necessary to get them inside cells, everybody knows what the target for MERS is, it is the core spike protein, which is one of things that targets the cell receptor and allows it to get in. It's a single protein that can be used to induce an immune response.

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"t-cell receptor." Definitions.net. STANDS4 LLC, 2024. Web. 29 Apr. 2024. <https://www.definitions.net/definition/t-cell+receptor>.

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