Definitions for statins
statins

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1. statins

   Statins, also known as HMG-CoA reductase inhibitors, are a class of lipid-lowering medications that reduce illness and mortality in those who are at high risk of cardiovascular disease. They are the most common cholesterol-lowering drugs.Low-density lipoprotein (LDL) carriers of cholesterol play a key role in the development of atherosclerosis and coronary heart disease via the mechanisms described by the lipid hypothesis. Statins are effective in lowering LDL cholesterol and so are widely used for primary prevention in people at high risk of cardiovascular disease, as well as in secondary prevention for those who have developed cardiovascular disease.Side effects of statins include muscle pain, increased risk of diabetes mellitus, and abnormal blood levels of liver enzymes. Additionally, they have rare but severe adverse effects, particularly muscle damage. They inhibit the enzyme HMG-CoA reductase which plays a central role in the production of cholesterol. High cholesterol levels have been associated with cardiovascular disease.There are various forms of statins, some of which include atorvastatin, fluvastatin, lovastatin, pitavastatin, pravastatin, rosuvastatin, and simvastatin. Combination preparations of a statin and another agent, such as ezetimibe/simvastatin, are also available. The class is on the World Health Organization's List of Essential Medicines with simvastatin being the listed medicine. In 2005, sales were estimated at US$18.7 billion in the United States. The best-selling statin is atorvastatin, also known as Lipitor, which in 2003 became the best-selling pharmaceutical in history. The manufacturer Pfizer reported sales of US$12.4 billion in 2008. Due to patent expirations, several statins became available in 2016 as less expensive generics.

Anagrams for statins »

1. tanists

How to pronounce statins?

1. Alex

   US English

   David

   US English

   Mark

   US English

   Daniel

   British

   Libby

   British

   Mia

   British

   Karen

   Australian

   Hayley

   Australian

   Natasha

   Australian

   Veena

   Indian

   Priya

   Indian

   Neerja

   Indian

   Zira

   US English

   Oliver

   British

   Wendy

   British

   Fred

   US English

   Tessa

   South African

How to say statins in sign language?

Numerology

1. Chaldean Numerology

   The numerical value of statins in Chaldean Numerology is: 3

2. Pythagorean Numerology

   The numerical value of statins in Pythagorean Numerology is: 3

Examples of statins in a Sentence

1. Ambarish Pandey:

   Making sure that we can improve access to care and opportunities to get … on medications like statins is key to reduce the disparities.

2. Robert Atmar:

   Statins shouldn’t be stopped because they already have been shown to lead to significant benefits such as decreased mortality due to cardiovascular events, patients should also continue to get vaccinated against influenza because it is still the best way to prevent getting sick.

3. Lori Daniels:

   As with any observational study, we cannot say for certain that the associations we describe between statin use and reduced severity of COVID-19 infection are definitely due to the statins themselves; however, we can now say with very strong evidence that they may play a role in substantially lowering a patient’s risk of death from COVID-19, we hope that our research findings are an incentive for patients to continue with their medication.

4. Leslie Cho:

   Patients who have had heart attacks need to recognize that statins actually prevent not only( repeat hospitalizations) but death.

5. Steven Nissen:

   I see heart patients that come in with terrible histories, multiple myocardial infarction, sometimes bypass surgery, many stents and they say, ‘Doctor, I’ve tried multiple statins, but whenever I take a statin, my muscles hurt, or they’re weak. I can’t walk upstairs. I just can’t tolerate these drugs,’ we do need alternatives for these patients.

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References

1. ^ Wikipedia
   https://en.wikipedia.org/wiki/Statins