Definitions for rifampicin
ri·fampicin

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1. rifampicinnoun

   rifampin

WikipediaRate this definition:0.0 / 0 votes

1. Rifampicin

   Rifampicin, also known as rifampin, is an ansamycin antibiotic used to treat several types of bacterial infections, including tuberculosis (TB), Mycobacterium avium complex, leprosy, and Legionnaires’ disease. It is almost always used together with other antibiotics with two notable exceptions: when given as a "preferred treatment that is strongly recommended" for latent TB infection; and when used as post-exposure prophylaxis to prevent Haemophilus influenzae type b and meningococcal disease in people who have been exposed to those bacteria. Before treating a person for a long period of time, measurements of liver enzymes and blood counts are recommended. Rifampicin may be given either by mouth or intravenously.Common side effects include nausea, vomiting, diarrhea, and loss of appetite. It often turns urine, sweat, and tears a red or orange color. Liver problems or allergic reactions may occur. It is part of the recommended treatment of active tuberculosis during pregnancy, though its safety in pregnancy is not known. Rifampicin is of the rifamycin group of antibiotics. It works by decreasing the production of RNA by bacteria.Rifampicin was discovered in 1965, marketed in Italy in 1968, and approved in the United States in 1971. It is on the World Health Organization's List of Essential Medicines. The World Health Organization classifies rifampicin as critically important for human medicine. It is available as a generic medication. Rifampicin is made by the soil bacterium Amycolatopsis rifamycinica.

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1. Rifampicin

   Rifampicin or rifampin is a bactericidal antibiotic drug of the rifamycin group. It is a semisynthetic compound derived from Amycolatopsis rifamycinica. Rifampicin may be abbreviated R, RMP, RA, RF, or RIF. In 1957, a soil sample from a pine forest on the French Riviera was brought for analysis to the Lepetit Pharmaceuticals research lab in Milan, Italy. There, a research group headed by Prof. Piero Sensi and Dr. Maria Teresa Timbal discovered a new bacterium. This new species appeared immediately of great scientific interest since it was producing a new class of molecules with antibiotic activity. Because Sensi, Timbal and the researchers were particularly fond of the French crime story Rififi, they decided to call these compounds "rifamycins". After two years of attempts to obtain more stable semisynthetic products, a new molecule with high efficacy and good tolerability was produced in 1959 and was named "rifampicin". Rifampicin is also known as rifaldazine, R/AMP, rofact, and rifampin in the United States. There are various types of rifamycins from which this is derived, but the rifampicin form, with a 4-methyl-1-piperazinaminyl group, is by far the most clinically effective.

How to pronounce rifampicin?

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Numerology

1. Chaldean Numerology

   The numerical value of rifampicin in Chaldean Numerology is: 7

2. Pythagorean Numerology

   The numerical value of rifampicin in Pythagorean Numerology is: 8

Examples of rifampicin in a Sentence

1. Fahimeh Sasan:

   For example, rifampicin and rifabutin which can be used to treat or prevent diseases including tuberculosis and meningitis.

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References

1. ^ Wiktionary
   https://en.wiktionary.org/wiki/Rifampicin
2. ^ Wikipedia
   https://en.wikipedia.org/wiki/Rifampicin
3. ^ Wikidata
   https://www.wikidata.org/w/index.php?search=rifampicin