Definitions for reuptakeriˈʌpˌteɪk
This page provides all possible meanings and translations of the word reuptake
Random House Webster's College Dictionary
the reabsorption of a chemical into the cell that released it.
Category: Chemistry, Biochemistry
Origin of reuptake:
a process of using up or consuming again
"psychopharmacologists discovered that amine reuptake is a process that inactivates monoamine neurotransmitters"
A second or subsequent uptake
Specifically, the reabsorption of a neurotransmitter by a neuron after the transmission of a neural impulse across a synapse
Reuptake, or re-uptake, is the reabsorption of a neurotransmitter by a neurotransmitter transporter of a pre-synaptic neuron after it has performed its function of transmitting a neural impulse. Reuptake is necessary for normal synaptic physiology because it allows for the recycling of neurotransmitters and regulates the level of neurotransmitter present in the synapse, thereby controlling how long a signal resulting from neurotransmitter release lasts. Because neurotransmitters are too large and hydrophilic to diffuse through the membrane, specific transport proteins are necessary for the reabsorption of neurotransmitters. Much research, both biochemical and structural, has been performed to obtain clues about the mechanism of reuptake.
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