What does protospacer adjacent motif mean?
Definitions for protospacer adjacent motif
pro·to·spac·er adja·cent motif
This dictionary definitions page includes all the possible meanings, example usage and translations of the word protospacer adjacent motif.
Wikipedia
Protospacer adjacent motif
A protospacer adjacent motif (PAM) is a 2–6-base pair DNA sequence immediately following the DNA sequence targeted by the Cas9 nuclease in the CRISPR bacterial adaptive immune system. The PAM is a component of the invading virus or plasmid, but is not found in the bacterial host genome and hence is not a component of the bacterial CRISPR locus. Cas9 will not successfully bind to or cleave the target DNA sequence if it is not followed by the PAM sequence. PAM is an essential targeting component which distinguishes bacterial self from non-self DNA, thereby preventing the CRISPR locus from being targeted and destroyed by the CRISPR-associated nuclease.
Numerology
Chaldean Numerology
The numerical value of protospacer adjacent motif in Chaldean Numerology is: 8
Pythagorean Numerology
The numerical value of protospacer adjacent motif in Pythagorean Numerology is: 6
Translations for protospacer adjacent motif
From our Multilingual Translation Dictionary
- protospacer المجاورة عزرArabic
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"protospacer adjacent motif." Definitions.net. STANDS4 LLC, 2024. Web. 30 Apr. 2024. <https://www.definitions.net/definition/protospacer+adjacent+motif>.
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