What does posttranslational modification mean?
Definitions for posttranslational modification
post·trans·la·tion·al mod·i·fi·ca·tion
This dictionary definitions page includes all the possible meanings, example usage and translations of the word posttranslational modification.
Wiktionary
posttranslational modificationnoun
Any of several types of modification made to a protein subsequent to the translation phase of its biosynthesis
Wikidata
Posttranslational modification
Posttranslational modification is a step in protein biosynthesis. Proteins are created by ribosomes translating mRNA into polypeptide chains. These polypeptide chains undergo PTM, before becoming the mature protein product. A protein is a chain of amino acids. During protein synthesis, 20 different amino acids can be incorporated to become a protein. After translation, the posttranslational modification of amino acids extends the range of functions of the protein by attaching it to other biochemical functional groups, changing the chemical nature of an amino acid, or making structural changes. Also, enzymes may remove amino acids from the amino end of the protein, or cut the peptide chain in the middle. For instance, the peptide hormone insulin is cut twice after disulfide bonds are formed, and a propeptide is removed from the middle of the chain; the resulting protein consists of two polypeptide chains connected by disulfide bonds. Also, most nascent polypeptides start with the amino acid methionine because the "start" codon on mRNA also codes for this amino acid. This amino acid is usually taken off during post-translational modification.
Numerology
Chaldean Numerology
The numerical value of posttranslational modification in Chaldean Numerology is: 9
Pythagorean Numerology
The numerical value of posttranslational modification in Pythagorean Numerology is: 2
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"posttranslational modification." Definitions.net. STANDS4 LLC, 2024. Web. 30 Apr. 2024. <https://www.definitions.net/definition/posttranslational+modification>.
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