What does pernicious anaemia mean?

Definitions for pernicious anaemia
per·ni·cious anaemi·a

This dictionary definitions page includes all the possible meanings, example usage and translations of the word pernicious anaemia.

Princeton's WordNet

  1. pernicious anemia, pernicious anaemia, malignant anemia, malignant anaemianoun

    a chronic progressive anemia of older adults; thought to result from a lack of intrinsic factor (a substance secreted by the stomach that is responsible for the absorption of vitamin B12)

Wikipedia

  1. Pernicious anaemia

    Pernicious anemia is a type of vitamin B12 deficiency anemia, a disease in which not enough red blood cells are produced due to the malabsorption of vitamin B12. Malabsorption in pernicious anemia results from the lack or loss of intrinsic factor needed for the absorption of vitamin B12. Anemia is defined as a condition in which the blood has a lower than normal amount of red blood cells or hemoglobin. The onset can be gradual and no changes can be observed for a period of time.The most common initial symptoms are tiredness, and weakness. Other signs and symptoms of anemia include breathlessness, dizziness, a sore red tongue, lightheadedness, headaches, poor ability to exercise, cold hands and feet, low blood pressure, pale or yellow skin, chest pain, and an irregular heartbeat. The digestive tract may also be disturbed giving symptoms that can include nausea and vomiting, heartburn, upset stomach and loss of appetite. Pernicious anemia can cause osteoporosis and may lead to bone fractures. Symptoms of vitamin B12 deficiency can include numbness in the hands and feet, memory problems, blurred vision, trouble walking, poor balance, muscle weakness, impaired sense of taste and smell, poor reflexes, clumsiness, depression, and confusion. Without treatment, some of these problems may become permanent.Pernicious anemia occurs due to an autoimmune response that produces antibodies that attack the parietal cells in the stomach lining and prevents them from creating intrinsic factor. Malabsorption may also result from the surgical removal of all or part of the stomach or small intestine; from an inherited disorder or illnesses that damage the stomach lining. When suspected, diagnosis is made by blood tests initially a complete blood count, and occasionally, bone marrow tests. Blood tests may show fewer but larger red blood cells, low numbers of young red blood cells, low levels of vitamin B12, and antibodies to intrinsic factor.Pernicious anemia can be treated with intramuscular injections or pills of vitamin B12. Nasal sprays and gels are also available for those who have trouble swallowing pills. Treatment may need to be lifelong.Pernicious anemia due to autoimmune problems occurs in about one per 1000 people in the USA. Among those over the age of 60, about 2% have the condition. It more commonly affects people of northern European descent. Women are more commonly affected than men. With proper treatment, most people live normal lives. Due to a higher risk of stomach cancer, those with pernicious anemia should be checked regularly for this. The first clear description was by Thomas Addison in 1849. The term "pernicious" means "deadly", and this term came into use because, before the availability of treatment, the disease was often fatal.

ChatGPT

  1. pernicious anaemia

    Pernicious anaemia is a type of anaemia that occurs when the body is unable to absorb enough Vitamin B12 from the diet, leading to a deficiency. This is often due to a lack of intrinsic factor in the stomach, which is necessary for Vitamin B12 absorption. The deficiency in Vitamin B12 can lead to the production of abnormally large red blood cells that cannot function properly, causing symptoms such as fatigue, shortness of breath, and neurological problems. The disease is more common in older adults and is often treated with Vitamin B12 injections or supplements.

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Numerology

  1. Chaldean Numerology

    The numerical value of pernicious anaemia in Chaldean Numerology is: 5

  2. Pythagorean Numerology

    The numerical value of pernicious anaemia in Pythagorean Numerology is: 2

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"pernicious anaemia." Definitions.net. STANDS4 LLC, 2024. Web. 28 Apr. 2024. <https://www.definitions.net/definition/pernicious+anaemia>.

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