Definitions for perforin

This page provides all possible meanings and translations of the word perforin

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  1. perforin(Noun)

    A cytolytic protein found in natural killer cells

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  1. Perforin

    Perforin-1 is a protein that in humans is encoded by the PRF1 gene.

U.S. National Library of MedicineRate this definition:(0.00 / 0 votes)

  1. Perforin

    A calcium-dependent pore-forming protein synthesized in cytolytic LYMPHOCYTES and sequestered in secretory granules. Upon immunological reaction between a cytolytic lymphocyte and a target cell, perforin is released at the plasma membrane and polymerizes into transmembrane tubules (forming pores) which lead to death of a target cell.

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