What does partition coefficient mean?
Definitions for partition coefficient
par·ti·tion co·ef·fi·cient
This dictionary definitions page includes all the possible meanings, example usage and translations of the word partition coefficient.
Wiktionary
partition coefficientnoun
The ration of the equilibrium concentrations of a solute in two immiscible solvents
Wikidata
Partition coefficient
In the physical sciences, a partition- or distribution-coefficient is the ratio of concentrations of a compound in a mixture of two immiscible phases at equilibrium. These coefficients are a measure of the difference in solubility of the compound in these two phases. In the chemical and pharmaceutical sciences, the two phases are often restricted to mean two immiscible solvents. In this context, a partition coefficient is the ratio of concentrations of a compound in the two phases of a mixture of two immiscible liquids at equilibrium. Normally one of the solvents chosen is water while the second is hydrophobic such as octanol. Hence both the partition and distribution coefficient are measures of how hydrophilic or hydrophobic a chemical substance is. In medical practice, partition coefficients are useful for example in estimating distribution of drugs within the body. Hydrophobic drugs with high octanol/water partition coefficients are preferentially distributed to hydrophobic compartments such as lipid bilayers of cells while hydrophilic drugs preferentially are found in hydrophilic compartments such as blood serum.
Numerology
Chaldean Numerology
The numerical value of partition coefficient in Chaldean Numerology is: 2
Pythagorean Numerology
The numerical value of partition coefficient in Pythagorean Numerology is: 1
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"partition coefficient." Definitions.net. STANDS4 LLC, 2024. Web. 29 Apr. 2024. <https://www.definitions.net/definition/partition+coefficient>.
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