Definitions for paroxetine
parox·e·tine

WiktionaryRate this definition:0.0 / 0 votes

1. paroxetinenoun

   an antidepressant drug, Paxil.

WikipediaRate this definition:0.0 / 0 votes

1. Paroxetine

   Paroxetine, sold under the brand names Paxil and Seroxat among others, is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. It is used to treat major depressive disorder, obsessive-compulsive disorder, panic disorder, social anxiety disorder, posttraumatic stress disorder, generalized anxiety disorder and premenstrual dysphoric disorder. It has also been used in the treatment of premature ejaculation and hot flashes due to menopause. It is taken by mouth.Common side effects include drowsiness, dry mouth, loss of appetite, sweating, trouble sleeping, and sexual dysfunction. Serious side effects may include suicidal thoughts in those under the age of 25, serotonin syndrome, and mania. While the rate of side effects appears similar compared to other SSRIs and SNRIs, antidepressant discontinuation syndromes may occur more often. Use in pregnancy is not recommended, while use during breastfeeding is relatively safe. It is believed to work by blocking the re-uptake of the chemical serotonin by neurons in the brain.Paroxetine was approved for medical use in the United States in 1992 and initially sold by GlaxoSmithKline. It is on the World Health Organization's List of Essential Medicines. It is available as a generic medication. In 2020, it was the 82nd most commonly prescribed medication in the United States, with more than 9 million prescriptions. In 2018, it was in the top 10 of most prescribed antidepressants in the United States. In 2012, the United States Department of Justice fined GlaxoSmithKline $3 billion for withholding data, unlawfully promoting use in those under 18, and preparing an article that misleadingly reported the effects of paroxetine in adolescents with depression following its clinical trial study 329.

WikidataRate this definition:0.0 / 0 votes

1. Paroxetine

   Paroxetine is an antidepressant drug of the SSRI type. Paroxetine is used to treat major depression, obsessive-compulsive disorder, panic disorder, social anxiety, posttraumatic stress disorder, and generalized anxiety disorder in adult outpatients. Marketing of the drug began in 1992 by the pharmaceutical company SmithKline Beecham, now GlaxoSmithKline. Generic formulations have been available since 2003 when the patent expired. In adults, the efficacy of paroxetine for depression is comparable to that of older tricyclic antidepressants, with fewer side effects and lower toxicity. Differences with newer antidepressants are subtler and mostly confined to side effects. It shares the common side effects and contraindications of other SSRIs, with high rates of nausea, somnolence, and sexual side effects. Paroxetine is associated with clinically significant weight gain. Pediatric trials of paroxetine for depression did not demonstrate statistical efficacy better than placebo. Discontinuing paroxetine is associated with a high risk of withdrawal syndrome. Because of the increased risk of birth defects, pregnant women or women planning to become pregnant are recommended to consult with their physician.

U.S. National Library of MedicineRate this definition:0.0 / 0 votes

1. Paroxetine

   A serotonin uptake inhibitor that is effective in the treatment of depression.

How to pronounce paroxetine?

1. Alex

   US English

   David

   US English

   Mark

   US English

   Daniel

   British

   Libby

   British

   Mia

   British

   Karen

   Australian

   Hayley

   Australian

   Natasha

   Australian

   Veena

   Indian

   Priya

   Indian

   Neerja

   Indian

   Zira

   US English

   Oliver

   British

   Wendy

   British

   Fred

   US English

   Tessa

   South African

How to say paroxetine in sign language?

Numerology

1. Chaldean Numerology

   The numerical value of paroxetine in Chaldean Numerology is: 7

2. Pythagorean Numerology

   The numerical value of paroxetine in Pythagorean Numerology is: 1

Examples of paroxetine in a Sentence

1. Roy Perlis:

   We have multiple good treatment options for depression – including medications and certain kinds of talk therapy, for women who do need medication treatment, there are multiple alternatives to paroxetine.

Popularity rank by frequency of use

References

1. ^ Wiktionary
   https://en.wiktionary.org/wiki/Paroxetine
2. ^ Wikipedia
   https://en.wikipedia.org/wiki/Paroxetine
3. ^ Wikidata
   https://www.wikidata.org/w/index.php?search=paroxetine