What does paracaspase mean?

Definitions for paracaspase
para·cas·pase

This dictionary definitions page includes all the possible meanings, example usage and translations of the word paracaspase.


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Wiktionary

  1. paracaspasenoun

    Any of a family of caspases found in animals and slime moulds

Wikidata

  1. Paracaspase

    Paracaspases are proteins related to caspases present in animals and slime mold, in contrast to metacaspases, which are present in plants, fungi, and "protists". Paracaspases are more similar to caspases than metacaspases are, indicating that this group of proteases diverged from caspases from a common metacaspase ancestor. The phylogenetic distribution is a bit confusing, since slime mold diverged earlier than the animal/fungal split. Paracaspase has been first identified in a recurrent t chromosomal translocation associated with a subset of MALT lymphoma. This leads to a fusion oncoprotein consisting of the carboxyl terminus of MALT1 and the amino terminus of c-IAP2. Genetic ablation of the paracaspase gene is mice and biochemical studies have shown that paracaspase is a crucial protein for T and B lymphocytes activation. It has an important role in the activation of the transcription factor NF-κB, in the production of interleukin-2 and in T and B lymphocytes proliferation In addition, a role for paracaspase has been shown in the innate immune response mediated by the zymosan receptor Dectin-1 in macrophages and dendritic cells, and in response to the stimulation of certain G protein-coupled receptors.

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Numerology

  1. Chaldean Numerology

    The numerical value of paracaspase in Chaldean Numerology is: 9

  2. Pythagorean Numerology

    The numerical value of paracaspase in Pythagorean Numerology is: 1

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"paracaspase." Definitions.net. STANDS4 LLC, 2024. Web. 8 May 2024. <https://www.definitions.net/definition/paracaspase>.

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