What does nucleotidase mean?
Definitions for nucleotidase
nu·cleoti·dase
This dictionary definitions page includes all the possible meanings, example usage and translations of the word nucleotidase.
Wiktionary
nucleotidasenoun
Any enzyme that catalyzes the hydrolysis or a nucleotide to a nucleoside and phosphate
Wikipedia
Nucleotidase
A nucleotidase is a hydrolytic enzyme that catalyzes the hydrolysis of a nucleotide into a nucleoside and a phosphate. A nucleotide + H2O = a nucleoside + phosphateFor example, it converts adenosine monophosphate to adenosine, and guanosine monophosphate to guanosine. Nucleotidases have an important function in digestion in that they break down consumed nucleic acids.
Wikidata
Nucleotidase
A nucleotidase is a hydrolytic enzyme that catalyzes the hydrolysis of a nucleotide into a nucleoside and a phosphate. For example, they convert adenosine monophosphate to adenosine, and guanosine monophosphate to guanosine. They have an important function in digestion in that they break down consumed nucleic acids. They can be divided into two categories, based upon the end which is hydrolyzed: ⁕EC 3.1.3.5: 5'-nucleotidase - NT5C, NT5C1A, NT5C1B, NT5C2, NT5C3 ⁕EC 3.1.3.6: 3'-nucleotidase - NT3 5' nucleotidases cleave off the phosphate from the 5' end of the sugar moiety. They can be classified into various kinds depending on their substrate preferences and subcellular localization. Membrane bound 5' nucleotidases displays specificity towards adenosine monophosphates and are predominantly involved in the salvage of preformed nucleotides and in signal transduction cascades involving purinergic receptors. Soluble 5' nucleotidases are all known to belong to the haloacid dehalogenase superfamily of enzymes which are two domain proteins characterised by a modified Rossman fold as the core and variable cap or hood. The soluble forms are further subclassified based on the criterion mentioned above. mdN and cdN are mitochondrial and cytosolic 5'-3' pyrimidine nucleotidases. cN-I is a cytosolic nucleotidase characterized by its affinity towards AMP as its substrate.cN-II is identified by its affinity towards either IMP or GMP or both. cN-III is a pyrimidine 5' nucleotidase. 5' nucleotidases are involved in varied functions like cell-cell communication, nucleic acid repair, purine salvage pathway for the synthesis of nucleotides, signal transduction, membrane transport etc.
Numerology
Chaldean Numerology
The numerical value of nucleotidase in Chaldean Numerology is: 2
Pythagorean Numerology
The numerical value of nucleotidase in Pythagorean Numerology is: 2
Popularity rank by frequency of use
Translation
Find a translation for the nucleotidase definition in other languages:
Select another language:
- - Select -
- 简体中文 (Chinese - Simplified)
- 繁體中文 (Chinese - Traditional)
- Español (Spanish)
- Esperanto (Esperanto)
- 日本語 (Japanese)
- Português (Portuguese)
- Deutsch (German)
- العربية (Arabic)
- Français (French)
- Русский (Russian)
- ಕನ್ನಡ (Kannada)
- 한국어 (Korean)
- עברית (Hebrew)
- Gaeilge (Irish)
- Українська (Ukrainian)
- اردو (Urdu)
- Magyar (Hungarian)
- मानक हिन्दी (Hindi)
- Indonesia (Indonesian)
- Italiano (Italian)
- தமிழ் (Tamil)
- Türkçe (Turkish)
- తెలుగు (Telugu)
- ภาษาไทย (Thai)
- Tiếng Việt (Vietnamese)
- Čeština (Czech)
- Polski (Polish)
- Bahasa Indonesia (Indonesian)
- Românește (Romanian)
- Nederlands (Dutch)
- Ελληνικά (Greek)
- Latinum (Latin)
- Svenska (Swedish)
- Dansk (Danish)
- Suomi (Finnish)
- فارسی (Persian)
- ייִדיש (Yiddish)
- հայերեն (Armenian)
- Norsk (Norwegian)
- English (English)
Word of the Day
Would you like us to send you a FREE new word definition delivered to your inbox daily?
Citation
Use the citation below to add this definition to your bibliography:
Style:MLAChicagoAPA
"nucleotidase." Definitions.net. STANDS4 LLC, 2024. Web. 25 Apr. 2024. <https://www.definitions.net/definition/nucleotidase>.
Discuss these nucleotidase definitions with the community:
Report Comment
We're doing our best to make sure our content is useful, accurate and safe.
If by any chance you spot an inappropriate comment while navigating through our website please use this form to let us know, and we'll take care of it shortly.
Attachment
You need to be logged in to favorite.
Log In