Definitions for niacinamideˌnaɪ əˈsɪn əˌmaɪd
This page provides all possible meanings and translations of the word niacinamide
Random House Webster's College Dictionary
ni•a•cin•a•mideˌnaɪ əˈsɪn əˌmaɪd(n.)
Origin of niacinamide:
The amide of niacin
U.S. National Library of Medicine
An important compound functioning as a component of the coenzyme NAD. Its primary significance is in the prevention and/or cure of blacktongue and PELLAGRA. Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and it therefore must be supplemented through dietary intake.
The active form of vitamin B3 and a component of the coenzyme nicotinamide adenine dinucleotide (NAD). Niacinamide acts as a chemo- and radio-sensitizing agent by enhancing tumor blood flow, thereby reducing tumor hypoxia. This agent also inhibits poly(ADP-ribose) polymerases, enzymes involved in the rejoining of DNA strand breaks induced by radiation or chemotherapy.
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