Definitions for niacinamideˌnaɪ əˈsɪn əˌmaɪd
This page provides all possible meanings and translations of the word niacinamide
Random House Webster's College Dictionary
ni•a•cin•a•mideˌnaɪ əˈsɪn əˌmaɪd(n.)
Origin of niacinamide:
The amide of niacin
U.S. National Library of Medicine
An important compound functioning as a component of the coenzyme NAD. Its primary significance is in the prevention and/or cure of blacktongue and PELLAGRA. Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and it therefore must be supplemented through dietary intake.
Nicotinamide, also known as niacinamide and nicotinic amide, is the amide of nicotinic acid. Nicotinamide is a water-soluble vitamin and is part of the vitamin B group. Nicotinic acid, also known as niacin, is converted to nicotinamide in vivo, and, though the two are identical in their vitamin functions, nicotinamide does not have the same pharmacological and toxic effects of niacin, which occur incidental to niacin's conversion. Thus nicotinamide does not reduce cholesterol or cause flushing, although nicotinamide may be toxic to the liver at doses exceeding 3 g/day for adults. In cells, niacin is incorporated into nicotinamide adenine dinucleotide and nicotinamide adenine dinucleotide phosphate, although the pathways for nicotinic acid amide and nicotinic acid are very similar. NAD+ and NADP+ are coenzymes in a wide variety of enzymatic oxidation-reduction reactions. It's produced by the aqueous aminolysis of 3-cyanopyridine and subsequent crystallization.
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